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Items: 20

1.

Inhibition of melanoma growth by small molecules that promote the mitochondrial localization of ATF2.

Varsano T, Lau E, Feng Y, Garrido M, Milan L, Heynen-Genel S, Hassig CA, Ronai ZA.

Clin Cancer Res. 2013 May 15;19(10):2710-22. doi: 10.1158/1078-0432.CCR-12-2689. Epub 2013 Apr 15.

2.

Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK.

Mace PD, Wallez Y, Egger MF, Dobaczewska MK, Robinson H, Pasquale EB, Riedl SJ.

Nat Commun. 2013;4:1681. doi: 10.1038/ncomms2687.

3.

CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoire.

Wu S, Zhu W, Nhan T, Toth JI, Petroski MD, Wolf DA.

Nat Commun. 2013;4:1642. doi: 10.1038/ncomms2636.

4.

The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity.

Qi J, Tripathi M, Mishra R, Sahgal N, Fazli L, Ettinger S, Placzek WJ, Claps G, Chung LW, Bowtell D, Gleave M, Bhowmick N, Ronai ZA.

Cancer Cell. 2013 Mar 18;23(3):332-46. doi: 10.1016/j.ccr.2013.02.016. Erratum in: Cancer Cell. 2013 Jun 10;23(6):853. Fazil, Ladan [corrected to Fazli, Ladan].

5.

Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.

Incerti M, Tognolini M, Russo S, Pala D, Giorgio C, Hassan-Mohamed I, Noberini R, Pasquale EB, Vicini P, Piersanti S, Rivara S, Barocelli E, Mor M, Lodola A.

J Med Chem. 2013 Apr 11;56(7):2936-47. doi: 10.1021/jm301890k. Epub 2013 Mar 22.

6.

Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis.

McDonough PM, Maciejewski-Lenoir D, Hartig SM, Hanna RA, Whittaker R, Heisel A, Nicoll JB, Buehrer BM, Christensen K, Mancini MG, Mancini MA, Edwards DP, Price JH.

PLoS One. 2013;8(2):e55511. doi: 10.1371/journal.pone.0055511. Epub 2013 Feb 6.

7.

HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery.

Wu B, Zhang Z, Noberini R, Barile E, Giulianotti M, Pinilla C, Houghten RA, Pasquale EB, Pellecchia M.

Chem Biol. 2013 Jan 24;20(1):19-33. doi: 10.1016/j.chembiol.2012.10.015.

8.

Single-particle EM reveals extensive conformational variability of the Ltn1 E3 ligase.

Lyumkis D, Doamekpor SK, Bengtson MH, Lee JW, Toro TB, Petroski MD, Lima CD, Potter CS, Carragher B, Joazeiro CA.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1702-7. doi: 10.1073/pnas.1210041110. Epub 2013 Jan 14.

9.

Design, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4.

Duggineni S, Mitra S, Noberini R, Han X, Lin N, Xu Y, Tian W, An J, Pasquale EB, Huang Z.

Biochem Pharmacol. 2013 Feb 15;85(4):507-13. doi: 10.1016/j.bcp.2012.12.005. Epub 2012 Dec 17.

10.

The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas.

Binda E, Visioli A, Giani F, Lamorte G, Copetti M, Pitter KL, Huse JT, Cajola L, Zanetti N, DiMeco F, De Filippis L, Mangiola A, Maira G, Anile C, De Bonis P, Reynolds BA, Pasquale EB, Vescovi AL.

Cancer Cell. 2012 Dec 11;22(6):765-80. doi: 10.1016/j.ccr.2012.11.005.

11.

NSP-CAS Protein Complexes: Emerging Signaling Modules in Cancer.

Wallez Y, Mace PD, Pasquale EB, Riedl SJ.

Genes Cancer. 2012 May;3(5-6):382-93. doi: 10.1177/1947601912460050.

12.

Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection.

Kuang E, Okumura CY, Sheffy-Levin S, Varsano T, Shu VC, Qi J, Niesman IR, Yang HJ, López-Otín C, Yang WY, Reed JC, Broday L, Nizet V, Ronai ZA.

PLoS Genet. 2012;8(10):e1003007. doi: 10.1371/journal.pgen.1003007. Epub 2012 Oct 18.

13.

A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924.

Toth JI, Yang L, Dahl R, Petroski MD.

Cell Rep. 2012 Apr 19;1(4):309-16. doi: 10.1016/j.celrep.2012.02.006. Epub 2012 Mar 19.

14.

Inhibition of Eph receptor-ephrin ligand interaction by tea polyphenols.

Noberini R, Koolpe M, Lamberto I, Pasquale EB.

Pharmacol Res. 2012 Oct;66(4):363-73. doi: 10.1016/j.phrs.2012.05.010. Epub 2012 Jun 28.

15.

ATF2 - at the crossroad of nuclear and cytosolic functions.

Lau E, Ronai ZA.

J Cell Sci. 2012 Jun 15;125(Pt 12):2815-24. doi: 10.1242/jcs.095000. Epub 2012 Jun 8.

16.

Translational homeostasis via the mRNA cap-binding protein, eIF4E.

Yanagiya A, Suyama E, Adachi H, Svitkin YV, Aza-Blanc P, Imataka H, Mikami S, Martineau Y, Ronai ZA, Sonenberg N.

Mol Cell. 2012 Jun 29;46(6):847-58. doi: 10.1016/j.molcel.2012.04.004. Epub 2012 May 10.

17.

Profiling Eph receptor expression in cells and tissues: a targeted mass spectrometry approach.

Noberini R, Rubio de la Torre E, Pasquale EB.

Cell Adh Migr. 2012 Mar-Apr;6(2):102-12. doi: 10.4161/cam.19620. Epub 2012 Mar 1.

18.

Regulation of transcriptome, translation, and proteome in response to environmental stress in fission yeast.

Lackner DH, Schmidt MW, Wu S, Wolf DA, Bähler J.

Genome Biol. 2012 Apr 18;13(4):R25. doi: 10.1186/gb-2012-13-4-r25.

19.

Drosophila: a model for understanding obesity and diabetic complications.

Teleman AA, Ratzenböck I, Oldham S.

Exp Clin Endocrinol Diabetes. 2012 Apr;120(4):184-5. doi: 10.1055/s-0032-1304566. Epub 2012 Mar 8. Review.

PMID:
22402943

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