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Neuroimaging Clin N Am. 2012 Nov;22(4):609-32. doi: 10.1016/j.nic.2012.04.004. Epub 2012 Aug 17.

Fungal infections of the central nervous system.

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1
Department of Radiology, Yale University Medical Center, New Haven, CT 06510, USA. mahan.mathur@gmail.com

Abstract

Fungal infections of the central nervous system (CNS) frequently occur in the immunocompromised or debilitated host. Imaging findings are non-specific but may be organized into extra-axial, parenchymal, and vascular categories. Furthermore, knowledge of fungal morphology may predict the imaging manifestations with large, hyphal species having a predilection for brain parenchymal involvement, while small, unicellular organisms typically result in meningitis. Advanced imaging techniques such as diffusion-weighted imaging, MR perfusion and MR spectroscopy, when combined with clinical findings, may help in differentiating fungal disease from other mimckers such as pyogenic infection or cystic metastases.

PMID:
23122259
DOI:
10.1016/j.nic.2012.04.004
[Indexed for MEDLINE]
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