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Items: 1 to 20 of 23


Epigenetic control of reprogramming and cellular differentiation.

Latella L, Palacios D, Forcales S, Puri PL.

Comp Funct Genomics. 2012;2012:538639. Epub 2012 Sep 17. No abstract available.


A Nodal-to-TGFβ cascade exerts biphasic control over cardiopoiesis.

Cai W, Guzzo RM, Wei K, Willems E, Davidovics H, Mercola M.

Circ Res. 2012 Sep 14;111(7):876-81. doi: 10.1161/CIRCRESAHA.112.270272. Epub 2012 Aug 7.


HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter.

Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F.

Chem Biol. 2012 Jul 27;19(7):806-18. doi: 10.1016/j.chembiol.2012.05.014.


Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.

Islas JF, Liu Y, Weng KC, Robertson MJ, Zhang S, Prejusa A, Harger J, Tikhomirova D, Chopra M, Iyer D, Mercola M, Oshima RG, Willerson JT, Potaman VN, Schwartz RJ.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13016-21. doi: 10.1073/pnas.1120299109. Epub 2012 Jul 23.


APJ acts as a dual receptor in cardiac hypertrophy.

Scimia MC, Hurtado C, Ray S, Metzler S, Wei K, Wang J, Woods CE, Purcell NH, Catalucci D, Akasaka T, Bueno OF, Vlasuk GP, Kaliman P, Bodmer R, Smith LH, Ashley E, Mercola M, Brown JH, Ruiz-Lozano P.

Nature. 2012 Aug 16;488(7411):394-8. doi: 10.1038/nature11263.


SIRT1 signaling as potential modulator of skeletal muscle diseases.

Tonkin J, Villarroya F, Puri PL, Vinciguerra M.

Curr Opin Pharmacol. 2012 Jun;12(3):372-6. doi: 10.1016/j.coph.2012.02.010. Epub 2012 Mar 7. Review.


Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: a structure-activity relationship study based on inhibitors for the Wnt response.

Lanier M, Schade D, Willems E, Tsuda M, Spiering S, Kalisiak J, Mercola M, Cashman JR.

J Med Chem. 2012 Jan 26;55(2):697-708. doi: 10.1021/jm2010223. Epub 2012 Jan 13.


Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia.

Kim H, Scimia MC, Wilkinson D, Trelles RD, Wood MR, Bowtell D, Dillin A, Mercola M, Ronai ZA.

Mol Cell. 2011 Nov 18;44(4):532-44. doi: 10.1016/j.molcel.2011.08.045.


Meeting review: cardiomyocyte regeneration and protection, La Jolla, California, June 2011.

Mercola M, Doevendans P.

J Cardiovasc Transl Res. 2012 Feb;5(1):100-5. doi: 10.1007/s12265-011-9323-x. Epub 2011 Nov 6. No abstract available.


Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells.

Stojic L, Jasencakova Z, Prezioso C, Stützer A, Bodega B, Pasini D, Klingberg R, Mozzetta C, Margueron R, Puri PL, Schwarzer D, Helin K, Fischle W, Orlando V.

Epigenetics Chromatin. 2011 Sep 5;4:16. doi: 10.1186/1756-8935-4-16.


Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm.

Willems E, Spiering S, Davidovics H, Lanier M, Xia Z, Dawson M, Cashman J, Mercola M.

Circ Res. 2011 Aug 5;109(4):360-4. doi: 10.1161/CIRCRESAHA.111.249540. Epub 2011 Jul 7.


Characterization of a novel angiogenic model based on stable, fluorescently labelled endothelial cell lines amenable to scale-up for high content screening.

Prigozhina NL, Heisel A, Wei K, Noberini R, Hunter EA, Calzolari D, Seldeen JR, Pasquale EB, Ruiz-Lozano P, Mercola M, Price JH.

Biol Cell. 2011 Oct 1;103(10):467-81. doi: 10.1042/BC20100146. Erratum in: Biol Cell. 2011 Dec 1;103(12):607.


Coordination of cell cycle, DNA repair and muscle gene expression in myoblasts exposed to genotoxic stress.

Simonatto M, Giordani L, Marullo F, Minetti GC, Puri PL, Latella L.

Cell Cycle. 2011 Jul 15;10(14):2355-63. Epub 2011 Jul 15.


MicroRNA programs in normal and aberrant stem and progenitor cells.

Arnold CP, Tan R, Zhou B, Yue SB, Schaffert S, Biggs JR, Doyonnas R, Lo MC, Perry JM, Renault VM, Sacco A, Somervaille T, Viatour P, Brunet A, Cleary ML, Li L, Sage J, Zhang DE, Blau HM, Chen C, Chen CZ.

Genome Res. 2011 May;21(5):798-810. doi: 10.1101/gr.111385.110. Epub 2011 Mar 30.


A chemical biology approach to myocardial regeneration.

Willems E, Lanier M, Forte E, Lo F, Cashman J, Mercola M.

J Cardiovasc Transl Res. 2011 Jun;4(3):340-50. doi: 10.1007/s12265-011-9270-6. Epub 2011 Mar 22. Review.


On proper linearization, construction and analysis of the Boyle-van't Hoff plots and correct calculation of the osmotically inactive volume.

Katkov II.

Cryobiology. 2011 Jun;62(3):232-41. doi: 10.1016/j.cryobiol.2011.02.006. Epub 2011 Mar 2.



Caretti G, Palacios D, Sartorelli V, Puri PL.

Cell Stem Cell. 2011 Mar 4;8(3):262-5. doi: 10.1016/j.stem.2011.02.012.


Cardiac muscle regeneration: lessons from development.

Mercola M, Ruiz-Lozano P, Schneider MD.

Genes Dev. 2011 Feb 15;25(4):299-309. doi: 10.1101/gad.2018411. Review.


Histone deacetylase inhibitors in the treatment of muscular dystrophies: epigenetic drugs for genetic diseases.

Consalvi S, Saccone V, Giordani L, Minetti G, Mozzetta C, Puri PL.

Mol Med. 2011 May-Jun;17(5-6):457-65. doi: 10.2119/molmed.2011.00049. Epub 2011 Feb 7. Review.


What your heart doth know.

Willems E, Mercola M.

Cell Stem Cell. 2011 Feb 4;8(2):124-6. doi: 10.1016/j.stem.2011.01.003.

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