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J Neurosci Methods. 2011 Oct 15;201(2):290-5. doi: 10.1016/j.jneumeth.2011.06.024. Epub 2011 Jul 6.

Head-mountable high speed camera for optical neural recording.

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  • 1School of Engineering and Applied Science, Yale University, New Haven, CT 06520, USA.

Abstract

We report a head-mountable CMOS camera for recording rapid neuronal activity in freely moving rodents using fluorescent activity reporters. This small, lightweight camera is capable of detecting small changes in light intensity (0.2% ΔI/I) at 500fps. The camera has a resolution of 32×32, sensitivity of 0.62V/lxs, conversion gain of 0.52μV/e(-) and well capacity of 2.1Me(-). The camera, containing intensity offset subtraction circuitry within the imaging chip, is part of a miniaturized epi-fluorescent microscope and represents a first generation, mobile scientific-grade, physiology imaging camera.

PMID:
21763348
PMCID:
PMC3179772
DOI:
10.1016/j.jneumeth.2011.06.024
[PubMed - indexed for MEDLINE]
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