Format

Send to

Choose Destination
Mycopathologia. 2011 Jul;172(1):47-53. doi: 10.1007/s11046-011-9391-0. Epub 2011 Jan 25.

Lymphocutaneous type of nocardiosis caused by Nocardia vinacea in a patient with polymyositis.

Author information

1
Department of Dermatology, Chiba University Graduate School of Medicine, Chuo-ku, Chiba, Japan. m-takahashi@faculty.chiba-u.jp

Abstract

We report a lymphocutaneous type of nocardiosis caused by Nocardia vinacea. A 62-year-old woman with polymyositis presented with some erythematous swellings and subcutaneous abscesses on her right middle finger and the dorsum of her hand, which had persisted for 2 weeks. Culturing of the excised nodule and pus revealed orange to orange-tan colonies with scanty whitish aerial mycelia. The isolate was identified as N. vinacea on the basis of its biochemical and chemotaxonomic characteristics and the results of molecular biological analysis. In our case, oral minocycline (MINO) and trimethoprim-sulfamethoxazole (TMP-SMX) for 7 weeks did not improve the clinical manifestation, even though in vitro susceptibility testing of the isolate predicted its susceptibility to MINO and TMP-SMX. Treatment with partial surgical excision followed by TMP-SMX and meropenem administration was effective. This is the first reported case of a lymphocutaneous type of nocardiosis caused by N. vinacea.

PMID:
21264517
DOI:
10.1007/s11046-011-9391-0
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center