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AIDS. 2007 May 31;21(9):1208-10.

WHO HIV clinical staging or CD4 cell counts for antiretroviral therapy eligibility assessment? An evaluation in rural Rakai district, Uganda.

Author information

1
Rakai Health Sciences Programme, Rakai, Uganda.

Abstract

The ability of WHO clinical staging to predict CD4 cell counts of 200 cells/microl or less was evaluated among 1221 patients screened for antiretroviral therapy (ART). Sensitivity was 51% and specificity was 88%. The positive predictive value was 64% and the negative predictive value was 81%. Clinical criteria missed half the patients with CD4 cell counts of 200 cells/microl or less, highlighting the importance of CD4 cell measurements for the scale-up of ART provision in resource-limited settings.

PMID:
17502733
DOI:
10.1097/QAD.0b013e32810c8dce
[Indexed for MEDLINE]

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