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Future Neurol. 2009 May 1;4(3):295-304.

Novel approaches to imaging epilepsy by MRI.

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1
Departments of Neurosurgery and Diagnostic Radiology, Yale University, 404 Tompkins East, 333 Cedar St, New Haven, CT 06525, USA ∎ hoby.hetherington@yale.edu.

Abstract

As the concept of a network of injury has emerged in the treatment of epilepsy, the importance of evaluating that network noninvasively has also grown. Recently, studies utilizing magnetic resonance spectroscopic imaging, manganese-enhanced MRI and functional (f)MRI measures of resting state connectivity have demonstrated their ability to detect injury and dysfunction in cerebral networks involved in the propagation of seizures. The ability to noninvasively detect neuronal injury and dysfunction throughout cerebral networks should improve surgical planning, provide guidance for placement of devices that target network propagation and provide insights into the mechanisms of recurrence following resective surgery.

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