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Physiology (Bethesda). 2010 Feb;25(1):41-9. doi: 10.1152/physiol.00033.2009.

Regulation of ionotropic glutamate receptors by their auxiliary subunits.

Author information

1
Program in Cellular Neuroscience, Neurodegeneration and Repair, Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA. Susumu.Tomita@yale.edu

Abstract

Glutamate receptors are major excitatory receptors in the brain. Recent findings have established auxiliary subunits of glutamate receptors as critical modulators of synaptic transmission, synaptic plasticity, and neurological disorder. The elucidation of the molecular rules governing glutamate receptors and subunits will improve our understanding of synapses and of neural-circuit regulation in the brain.

PMID:
20134027
PMCID:
PMC3010179
DOI:
10.1152/physiol.00033.2009
[Indexed for MEDLINE]
Free PMC Article
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