Format

Send to

Choose Destination
Cell. 2009 Oct 30;139(3):458-9. doi: 10.1016/j.cell.2009.10.016.

How to drive your helicase in a straight line.

Author information

1
Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University, New Haven, CT 06511, USA. anna.pyle@yale.edu

Abstract

Helicases are molecular motors that move along and remodel DNA, RNA, and associated protein complexes. Helicases are often directional. By analyzing crystal structures in complexes with RNA and ATP analogs, Thomsen and Berger (2009) now elucidate the molecular basis for unidirectional motion by the hexameric RNA helicase Rho.

PMID:
19879832
DOI:
10.1016/j.cell.2009.10.016
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center