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J Rehabil Med. 2009 Mar;41(4):256-61. doi: 10.2340/16501977-0315.

Pain reduction using transcranial electrostimulation: a double blind "active placebo" controlled trial.

Author information

  • 1Weinberg Child Development Center, Safra Children's Hospital at Sheba Medical Center, Affiliated to the Tel-Aviv University Sackler School of Medicine, Tel Hashomer, Israel. gabis@post.tau.ac.il

Abstract

OBJECTIVE:

To examine the efficacy of transcranial electrical stimulation a non-invasive method of reducing pain.

DESIGN:

A randomized, double-blind, placebo-controlled trial.

SUBJECTS:

A total of 119 patients with chronic pain.

METHODS:

Patients were treated with either transcranial electrical stimulation or an active placebo device. Short- and long-term follow-ups were evaluated for treatment efficacy with 4 ordinal scale variables: visual analogue scale (pain level), SLEEP (how often does pain disturb sleep), FREQ (frequency of pain) and MED (frequency of use of medications to relieve pain).

RESULTS:

Pain level decreased significantly in the transcranial electrical stimulation-treated group compared with the active-placebo group 3 weeks after the end of treatment (p = 0.0017 between groups). Other parameters did not demonstrate significant differences. Three months after the end of treatment this effect was maintained and other treatment parameters showed similar improvements.

CONCLUSION:

Transcranial electrical stimulation is an effective non-invasive method for pain relief. The active placebo device has a powerful effect on reported pain, which diminishes in the long-term. The involvement of possible neural mechanisms is discussed.

PMID:
19247545
DOI:
10.2340/16501977-0315
[PubMed - indexed for MEDLINE]
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