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J Neurooncol. 2008 Jan;86(1):57-60. Epub 2007 Oct 2.

CSF IgH gene rearrangement analysis in isolated post-transplant lymphoproliferative disorder of the central nervous system.

Author information

1
Department of Neurology and Neurosurgery, Yale University School of Medicine, 333 Cedar Street, TMP412, New Haven, CT 06510, USA. Joachim.baehring@yale.edu

Abstract

Isolated post-transplant lymphoproliferative disorder (PTLD) of the central nervous system is rare and its diagnosis can be challenging. A biopsy is usually required in order to distinguish the disease from opportunistic infections. We present a case in whom immunoglobulin heavy chain gene rearrangement analysis of cerebrospinal fluid (CSF) was instrumental in establishing the diagnosis.

PMID:
17909942
DOI:
10.1007/s11060-007-9429-9
[Indexed for MEDLINE]

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