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Actas Esp Psiquiatr. 2007 Nov-Dec;35(6):368-71.

Reliability study of the translation into Spanish of the PRIME Screen Questionnaire for Prodromic Symtoms.

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Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón, de la Fuente, México.



A fundamental precondition for early intervention in schizophrenia is accurate detection of prodromal states, that is, sign and symptom constellations that predict the onset of psychosis in persons with no prior background. Several structured interviews have been designed for the detection of prodromal subjects.


To translate and determine the reliability of the PRIME Screen in an adolescent community sample in México City.


A total of 532 adolescents of a technical-industrial educational center of México City were included for the study. All the subjects were administered the PRIME Screen Questionnaire of Prodromal Symptoms.


A total of 98 subjects (18.4%) reported one or more prodromal symptoms. The results of the factorial analysis showed that the PRIME Screen questionnaire is conformed by three factors that explained 59.3% of the variance. Internal consistency of the instrument was of 0.88.


Our results on the exploratory factor analysis show that the items of the questionnaire are grouped into three main areas called: a) alteration of setting; b) sensorial-perceptual abnormalities, and c) alterations of self-skills. The Prodromal Symptoms Screen Questionnaire is an instrument with adequate clinimetric behavior that may be effective to conduct community-wide screening of adolescents for prodromal symptoms.

[Indexed for MEDLINE]

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