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Science. 2007 Apr 20;316(5823):397.

piRNAs in the germ line.

Author information

1
Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT 06510, USA. haifan.lin@yale.edu

Abstract

Small noncoding RNAs have emerged as potent regulators of gene expression at both transcriptional and posttranscriptional levels. Recently, a class of small RNAs that interact with Piwi proteins has been discovered in the mammalian germ line and Drosophila. These Piwi-interacting RNAs (piRNAs) represent a distinct small RNA pathway.

PMID:
17446387
DOI:
10.1126/science.1137543
[Indexed for MEDLINE]
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