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Immunol Today. 1991 Aug;12(8):277-82.

T-cell recognition of myelin basic protein.

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1
Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA.

Abstract

Multiple sclerosis is a chronic inflammatory disease of the central nervous system which has been hypothesized to be autoimmune in nature. To test whether this is the case, Kai Wucherpfennig and colleagues have developed a set of criteria that must be met to satisfy the hypothesis. Here, they present these criteria and assess the extent to which studies to date satisfy them.

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PMID:
1716903
DOI:
10.1016/0167-5699(91)90126-E
[Indexed for MEDLINE]
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