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Exerc Sport Sci Rev. 2006 Oct;34(4):182-93.

Randomized controlled trials of physical activity and breast cancer prevention.

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Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT, USA.


Observational studies demonstrate that women who exercise have a lower risk of developing breast cancer compared with sedentary women, but clinical trials are necessary to demonstrate a decreased effect of exercise on breast cancer. This review presents a rationale for randomized controlled exercise trials for breast cancer prevention and proposes a construct for designing such trials.

[Indexed for MEDLINE]

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