Format

Send to

Choose Destination
An Pediatr (Barc). 2017 Dec;87(6):311-319. doi: 10.1016/j.anpedi.2016.10.016. Epub 2017 Mar 28.

[A prospective study to assess the burden of influenza-related hospitalizations and emergency department visits among children in Bilbao, Spain (2010-2011)].

[Article in Spanish]

Author information

1
Departamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España.
2
Departamento de Pediatría, Hospital Universitario de Basurto, Universidad del País Vasco (UPV/EHU), Bilbao, España. Electronic address: mariaisabel.garrotellanos@osakidetza.net.
3
Departamento Médico, GSK, Tres Cantos (Madrid), España.
4
CDOC-B, GSK, Bangalore, India.
5
GSK, Wavre, Bélgica.

Abstract

INTRODUCTION:

This study was undertaken to estimate the burden of morbidity associated with laboratory-confirmed influenza in children below 15 years of age.

PATIENTS AND METHODS:

Children presenting with acute respiratory infection and/or isolated fever at the Basurto University Hospital, Bilbao, Spain between November 2010 and May 2011 were included in this study (NCT01592799). Two nasopharyngeal secretion samples were taken from each; one for a rapid influenza diagnostic test in the emergency department, and the second for laboratory analysis using real-time polymerase chain reaction and viral culture.

RESULTS:

A total of 501 children were recruited, of whom 91 were hospitalized. Influenza diagnosis was confirmed in 131 children (26.1%); 120 of 410 (29.3%) treated as outpatients and 11 of 91 (12.1%) hospitalized children. A total of 370 of 501 children (73.9%) had no laboratory test positive for influenza. The proportion of subjects with other respiratory viruses was 145/501 (28.9%) cases and co-infection with the influenza virus plus another respiratory virus was detected in 7/501 (1.4%) cases. Influenza virus types were: A (H1N1 and H3N2) 53.2% (67/126); B (Victoria and Yamagata) 46.0% (58/126); A+B 0.8% (1/126). The median direct medical costs associated with each case of laboratory-confirmed influenza was €177.00 (N=131). No significant differences were observed between the medical costs associated with influenza A and B.

CONCLUSION:

Almost half of the cases were influenza virus B type. The administration of a vaccine containing influenza A and B types to children below 15 years of age might reduce the overall burden of the illness.

KEYWORDS:

Emergency department; España; Gripe; Hospitalización; Hospitalization; Influenza; Servicio de Urgencia; Spain

PMID:
28363360
DOI:
10.1016/j.anpedi.2016.10.016
Free full text

Supplemental Content

Full text links

Icon for Ediciones Doyma, S.L.
Loading ...
Support Center