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Gac Med Mex. 2006 Mar-Apr;142(2):113-20.

[Impact of the duration of untreated psychosis among patients with a first episode: a one year follow-up study].

[Article in Spanish]

Author information

1
Subdirección de Psiquiatría, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suarez, Mexico DF, México. rogelioapiquian@yahoo.com.mx

Abstract

BACKGROUND:

The delay on the onset of specific treatment has several prognostic implications for psychotic patients. Duration of untreated psychosis (DUP) has been considered a prognostic variable. A longer DUP has been associated with a poor clinical outcome.

OBJECTIVE:

To determine the DUP in a sample of first-episode psychotic patients and its relationship with recovery and relapse on a one-year follow-up study.

MATERIAL AND METHODS:

A sample of 66 first-episode psychotic patients was recruited and divided according to their diagnoses in affective and non-affective psychoses. Diagnoses were obtained with SCAN and DUP was registered for each patient. A clinical assessment for psychotic and affective symptoms was performed using standardized instruments.

RESULTS:

All patient studied showed clinical improvement during follow-up. Patients with a longer DUP showed poorer psychosocial adjustment and lower recovery indexes. Treatment suspension was the main variable associated with relapse.

CONCLUSIONS:

DUP is an important prognostic variable. Early detection programs are required to decrease the period between illness onset, diagnosis and treatment in first-episode psychotic patients.

PMID:
16711545
[Indexed for MEDLINE]

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