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J Nucl Med Technol. 2005 Dec;33(4):230-1.

Artifactual spinal metastases imaged by PET/CT: a case report.

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Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520-8042, USA.


A 55-y-old patient with multiple myeloma presented for restaging after chemotherapy and radiation. The patient had undergone vertebroplasty of multiple thoracic vertebrae because of painful compression fractures. The 18F-FDG PET images showed increased activity at the T8 and T10-T12 vertebral bodies. Comparison of the attenuation-corrected and non-attenuation-corrected images demonstrated that the activity was due to an artifact of attenuation correction. The CT scan correlated the sites of vertebroplasty to the 4 foci of increased uptake of 18F-FDG. The increasing use of vertebroplasty for malignant spinal fractures warrants vigilance for this artifact.

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