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Bol Med Hosp Infant Mex. 1992 May;49(5):309-12.

[Chromosomal translocation (2;13) in disseminated rhabdomyosarcoma].

[Article in Spanish]

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Departamento de Investigación en Genética Humana, Instituto Nacional de Pediatría, México, D.F.


A 12-year-old male with a disseminated alveolar rhabdomyosarcoma is reported. The diagnosis was difficult because of the clinical manifestations and the histological patterns of the bone marrow and a chest wall tumor. Diagnosis was confirmed through the histologic picture of a gum biopsy and the karyotype of the tumoral cells of the bone marrow. Chromosome study revealed a hypotetraploid cell line with the translocation (2;13) characteristic of this type of neoplasias. The usefulness of chromosome studies in solid tumors of childhood is emphasized.

[Indexed for MEDLINE]

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