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Curr Opin Neurobiol. 2005 Aug;15(4):431-6.

Recent progress towards understanding the synaptic ribbon.

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1
Department of Cellular and Molecular Physiology, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06511, USA.

Abstract

Neurons of the visual, auditory and vestibular systems that signal through graded changes in membrane potential rely upon synaptic ribbons for the exquisite control of neurotransmitter release. Although clearly important for tonic neurotransmission, the precise role of synaptic ribbons remains elusive. In recent years, several genetic, biochemical, electrophysiological and optical approaches have begun to shed light on the functions of these enigmatic organelles.

PMID:
16023852
DOI:
10.1016/j.conb.2005.07.005
[Indexed for MEDLINE]
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