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IEEE Trans Nanobioscience. 2005 Mar;4(1):121-7.

Microchip technology in ion-channel research.

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  • 1Department of Cellular and Molecular Physiology, Yale University, New Haven, CT 06520-8026, USA. fred.sigworth@yale.edu

Abstract

The electrical activity of living cells can be monitored in various ways, but for the study of ion channels and the drugs that affect them, the patch-clamp techniques are the most sensitive. Recent developments in microfabricated patch-clamp electrodes are reviewed, and technical challenges for the future are discussed.

PMID:
15816178
[PubMed - indexed for MEDLINE]
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