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Curr Biol. 2004 Oct 26;14(20):R898-900.

NF-kappaB signaling: flipping the switch with polyubiquitin chains.

Author information

1
Yale University, Department of Molecular Biophysics & Biochemistry, 266 Whitney Avenue, P.O. Box 208114 New Haven, Connecticut 06520-8114, USA.

Abstract

Protein modification by ubiquitin has emerged as an important cellular regulatory mechanism. Recent studies illustrate the surprising ways in which polyubiquitin chains are manipulated in the regulation of NF-kappaB signaling.

PMID:
15498483
DOI:
10.1016/j.cub.2004.09.074
[Indexed for MEDLINE]
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