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Am J Psychiatry. 1992 Mar;149(3):399-400.

Blood levels and acute response to bupropion.

Author information

1
Department of Psychiatry, University of Miami, FL 33136.

Abstract

Twenty-three patients with major depressive disorder were treated with bupropion in an open-design protocol. Fifteen (65.2%) of the 23 responded with a more than 50% decrease in scores on the Beck Depression Inventory. Patients with trough blood levels of 10-29 ng/ml had a significantly better response than those with trough levels of 30 ng/ml or more. This preliminary result warrants further, double-blind evaluation.

PMID:
1536282
DOI:
10.1176/ajp.149.3.399
[Indexed for MEDLINE]

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