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Bioorg Med Chem Lett. 2002 Dec 2;12(23):3463-6.

Inhibitors of NF-kappaB signaling: design and synthesis of a biotinylated isopanepoxydone affinity reagent.

Author information

1
Sterling Chemistry Laboratory, Yale University, New Haven, CT 06520, USA.

Abstract

A number of inhibitors of NF-kappaB signaling arising from our recent syntheses of isopanepoxydone and panepoxydone have been identified. Structure-activity data have been correlated to allow the design and synthesis of an affinity reagent for the isolation and identification of any relevant cellular target.

PMID:
12419384
[Indexed for MEDLINE]

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