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Mol Cell. 2002 Aug;10(2):218-9.

All signaling is local?

Author information

1
Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510, USA.

Abstract

The mechanism of signal transmission following ligand stimulation of receptor tyrosine kinases in living cells is poorly understood. Recent studies have visualized the spatio-temporal pattern of EGF signaling, indicating that receptor density is an important factor in the mechanism of lateral propagation of local EGF signaling.

PMID:
12191465
[Indexed for MEDLINE]
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