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Curr Biol. 2002 Mar 19;12(6):R203-5.

Molecular motors: single-molecule recordings made easy.

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1
Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr. 108, 01307 Dresden, Germany.

Abstract

A fusion protein of kinesin and gelsolin binds a short actin filament which can be visualized using a standard fluorescence microscope. This technique has provided new insight into the mechanism of kinesin action, and in principle it can be extended to allow single-molecule assays of any protein.

PMID:
11909546
[Indexed for MEDLINE]
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