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Chest. 2001 Feb;119(2):470-7.

Transcatheter embolotherapy of maternal pulmonary arteriovenous malformations during pregnancy.

Author information

1
Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Abstract

STUDY OBJECTIVES:

To determine if transcatheter embolotherapy is safe and effective for the treatment of pulmonary arteriovenous malformations during pregnancy.

DESIGN:

Prospective study.

SETTING:

Specialized hereditary hemorrhagic telangiectasia centers at Yale University School of Medicine and St. Michael's Hospital, University of Toronto.

PATIENTS:

Seven pregnant women (age range, 24 to 34 years; gestational age range, 16 to 36 weeks) undergoing transcatheter embolotherapy.

INTERVENTIONS:

Transcatheter embolotherapy in all patients.

MEASUREMENTS AND RESULTS:

Thirteen pulmonary arteriovenous malformations in seven patients were embolized with detachable silicone balloons and/or stainless steel coils without incident. The estimated fetal radiation dose ranged from < 50 to 220 mrad. No complications of pulmonary arteriovenous malformations occurred in any of the patients after transcatheter embolotherapy. The mothers went on to deliver healthy babies in all cases.

CONCLUSIONS:

Transcatheter embolotherapy of maternal pulmonary arteriovenous malformations performed by an experienced radiologist appears to be safe and effective after 16 weeks of gestational age.

PMID:
11171725
[Indexed for MEDLINE]
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