Format

Send to

Choose Destination
Proteins. 1999 Feb 1;34(2):220-3.

A modified definition of Sov, a segment-based measure for protein secondary structure prediction assessment.

Author information

1
Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, California 94551, USA.

Abstract

We present a measure for the evaluation of secondary structure prediction methods that is based on secondary structure segments rather than individual residues. The algorithm is an extension of the segment overlap measure Sov, originally defined by Rost et al. (J Mol Biol 1994;235:13-26). The new definition of Sov corrects the normalization procedure and improves Sov's ability to discriminate between similar and dissimilar segment distributions. The method has been comprehensively tested during the second Critical Assessment of Techniques for Protein Structure Prediction (CASP2). Here, we describe the underlying concepts, modifications to the original definition, and their significance.

PMID:
10022357
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center