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Items: 1 to 20 of 127


Zika Virus: Origins, Pathological Action, and Treatment Strategies.

Gorshkov K, Shiryaev SA, Fertel S, Lin YW, Huang CT, Pinto A, Farhy C, Strongin AY, Zheng W, Terskikh AV.

Front Microbiol. 2019 Jan 7;9:3252. doi: 10.3389/fmicb.2018.03252. eCollection 2018. Review.


Characterization and regulation of MT1-MMP cell surface-associated activity.

Pahwa S, Bhowmick M, Amar S, Cao J, Strongin AY, Fridman R, Weiss SJ, Fields GB.

Chem Biol Drug Des. 2019 Jun;93(6):1251-1264. doi: 10.1111/cbdd.13450. Epub 2018 Dec 19.


Coordinated histone modifications and chromatin reorganization in a single cell revealed by FRET biosensors.

Peng Q, Lu S, Shi Y, Pan Y, Limsakul P, Chernov AV, Qiu J, Chai X, Shi Y, Wang P, Ji Y, Li YJ, Strongin AY, Verkhusha VV, Izpisua Belmonte JC, Ren B, Wang Y, Chien S, Wang Y.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11681-E11690. doi: 10.1073/pnas.1811818115. Epub 2018 Nov 26.


Structural homology of myelin basic protein and muscarinic acetylcholine receptor: Significance in the pathogenesis of complex regional pain syndrome.

Shubayev VI, Strongin AY, Yaksh TL.

Mol Pain. 2018 Jan-Dec;14:1744806918815005. doi: 10.1177/1744806918815005. Epub 2018 Nov 5. Review.


Tissue inhibitors of metalloproteases strike a nerve.

Shubayev VI, Strongin AY.

Neural Regen Res. 2018 Nov;13(11):1890-1892. doi: 10.4103/1673-5374.239437. No abstract available.


Amino acid sequence conservation of the algesic fragment of myelin basic protein is required for its interaction with CDK5 and function in pain.

Chernov AV, Remacle AG, Hullugundi SK, Cieplak P, Angert M, Dolkas J, Shubayev VI, Strongin AY.

FEBS J. 2018 Sep;285(18):3485-3502. doi: 10.1111/febs.14623. Epub 2018 Aug 27.


Interaction of the cryptic fragment of myelin basic protein with mitochondrial voltage-dependent anion-selective channel-1 affects cell energy metabolism.

Remacle AG, Hullugundi SK, Dolkas J, Angert M, Cieplak P, Scott D, Chernov AV, Shubayev VI, Strongin AY.

Biochem J. 2018 Jul 31;475(14):2355-2376. doi: 10.1042/BCJ20180137.


Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury.

Remacle AG, Hullugundi SK, Dolkas J, Angert M, Chernov AV, Strongin AY, Shubayev VI.

J Neuroinflammation. 2018 Mar 20;15(1):89. doi: 10.1186/s12974-018-1123-7.


A sensitive and selective ELISA methodology quantifies a demyelination marker in experimental and clinical samples.

Remacle AG, Dolkas J, Angert M, Hullugundi SK, Chernov AV, Jones RCW 3rd, Shubayev VI, Strongin AY.

J Immunol Methods. 2018 Apr;455:80-87. doi: 10.1016/j.jim.2018.02.002. Epub 2018 Feb 8.


Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface.

Limsakul P, Peng Q, Wu Y, Allen ME, Liang J, Remacle AG, Lopez T, Ge X, Kay BK, Zhao H, Strongin AY, Yang XL, Lu S, Wang Y.

Cell Chem Biol. 2018 Apr 19;25(4):370-379.e4. doi: 10.1016/j.chembiol.2018.01.002. Epub 2018 Jan 27.


Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis.

Shiryaev SA, Mesci P, Pinto A, Fernandes I, Sheets N, Shresta S, Farhy C, Huang CT, Strongin AY, Muotri AR, Terskikh AV.

Sci Rep. 2017 Nov 17;7(1):15771. doi: 10.1038/s41598-017-15467-6.


Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists.

Shiryaev SA, Farhy C, Pinto A, Huang CT, Simonetti N, Elong Ngono A, Dewing A, Shresta S, Pinkerton AB, Cieplak P, Strongin AY, Terskikh AV.

Antiviral Res. 2017 Jul;143:218-229. doi: 10.1016/j.antiviral.2017.04.015. Epub 2017 Apr 29.


Matrix metalloproteinases - From the cleavage data to the prediction tools and beyond.

Cieplak P, Strongin AY.

Biochim Biophys Acta Mol Cell Res. 2017 Nov;1864(11 Pt A):1952-1963. doi: 10.1016/j.bbamcr.2017.03.010. Epub 2017 Mar 24. Review.


Active-site MMP-selective antibody inhibitors discovered from convex paratope synthetic libraries.

Nam DH, Rodriguez C, Remacle AG, Strongin AY, Ge X.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):14970-14975. doi: 10.1073/pnas.1609375114. Epub 2016 Dec 13.


Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis.

Remacle AG, Cieplak P, Nam DH, Shiryaev SA, Ge X, Strongin AY.

Oncotarget. 2017 Jan 10;8(2):2781-2799. doi: 10.18632/oncotarget.13157.


Reciprocal relationship between membrane type 1 matrix metalloproteinase and the algesic peptides of myelin basic protein contributes to chronic neuropathic pain.

Hong S, Remacle AG, Shiryaev SA, Choi W, Hullugundi SK, Dolkas J, Angert M, Nishihara T, Yaksh TL, Strongin AY, Shubayev VI.

Brain Behav Immun. 2017 Feb;60:282-292. doi: 10.1016/j.bbi.2016.11.003. Epub 2016 Nov 7.


Role of myelin auto-antigens in pain: a female connection.

Shubayev VI, Strongin AY, Yaksh TL.

Neural Regen Res. 2016 Jun;11(6):890-1. doi: 10.4103/1673-5374.184452. No abstract available.


Spinal activity of interleukin 6 mediates myelin basic protein-induced allodynia.

Ko JS, Eddinger KA, Angert M, Chernov AV, Dolkas J, Strongin AY, Yaksh TL, Shubayev VI.

Brain Behav Immun. 2016 Aug;56:378-89. doi: 10.1016/j.bbi.2016.03.003. Epub 2016 Mar 9.


Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer.

Alonso S, González B, Ruiz-Larroya T, Durán Domínguez M, Kato T, Matsunaga A, Suzuki K, Strongin AY, Gimènez-Bonafé P, Perucho M.

Clin Epigenetics. 2015 Dec 2;7:124. doi: 10.1186/s13148-015-0158-1. eCollection 2015.


Depletion of CG-Specific Methylation in Mycoplasma hyorhinis Genomic DNA after Host Cell Invasion.

Chernov AV, Reyes L, Peterson S, Strongin AY.

PLoS One. 2015 Nov 6;10(11):e0142529. doi: 10.1371/journal.pone.0142529. eCollection 2015.

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