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Items: 1 to 20 of 114

1.

Methylomic changes in response to micronutrient supplementation and MTHFR genotype.

Stevens AJ, Rucklidge JJ, Darling KA, Eggleston MJ, Pearson JF, Kennedy MA.

Epigenomics. 2018 Sep;10(9):1201-1214. doi: 10.2217/epi-2018-0029. Epub 2018 Sep 5.

2.

The effect of inflammation-related lifestyle exposures and interactions with gene variants on long interspersed nuclear element-1 DNA methylation.

Gogna P, O'Sullivan DE, King WD.

Epigenomics. 2018 Jun;10(6):785-796. doi: 10.2217/epi-2017-0164. Epub 2018 Jun 11.

PMID:
29888958
3.

Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects.

Christensen KE, Bahous RH, Hou W, Deng L, Malysheva OV, Arning E, Bottiglieri T, Caudill MA, Jerome-Majewska LA, Rozen R.

J Nutr. 2018 Apr 1;148(4):501-509. doi: 10.1093/jn/nxy013.

PMID:
29659962
4.

Methylene-tetrahydrofolate reductase contributes to allergic airway disease.

Eyring KR, Pedersen BS, Maclean KN, Stabler SP, Yang IV, Schwartz DA.

PLoS One. 2018 Jan 12;13(1):e0190916. doi: 10.1371/journal.pone.0190916. eCollection 2018.

5.

Impact of folic acid intake during pregnancy on genomic imprinting of IGF2/H19 and 1-carbon metabolism.

Tserga A, Binder AM, Michels KB.

FASEB J. 2017 Dec;31(12):5149-5158. doi: 10.1096/fj.201601214RR. Epub 2017 Aug 4.

6.

High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.

Bahous RH, Jadavji NM, Deng L, Cosín-Tomás M, Lu J, Malysheva O, Leung KY, Ho MK, Pallàs M, Kaliman P, Greene NDE, Bedell BJ, Caudill MA, Rozen R.

Hum Mol Genet. 2017 Mar 1;26(5):888-900. doi: 10.1093/hmg/ddx004.

7.

Guidelines for diagnosis and management of the cobalamin-related remethylation disorders cblC, cblD, cblE, cblF, cblG, cblJ and MTHFR deficiency.

Huemer M, Diodato D, Schwahn B, Schiff M, Bandeira A, Benoist JF, Burlina A, Cerone R, Couce ML, Garcia-Cazorla A, la Marca G, Pasquini E, Vilarinho L, Weisfeld-Adams JD, Kožich V, Blom H, Baumgartner MR, Dionisi-Vici C.

J Inherit Metab Dis. 2017 Jan;40(1):21-48. doi: 10.1007/s10545-016-9991-4. Epub 2016 Nov 30. Review.

8.

Folate deficiency and over-supplementation causes impaired folate metabolism: Regulation and adaptation mechanisms in Caenorhabditis elegans.

Ortbauer M, Ripper D, Fuhrmann T, Lassi M, Auernigg-Haselmaier S, Stiegler C, König J.

Mol Nutr Food Res. 2016 Apr;60(4):949-56. doi: 10.1002/mnfr.201500819. Epub 2016 Jan 19.

PMID:
27061234
9.

Effect of in ovo feeding of folic acid on the folate metabolism, immune function and epigenetic modification of immune effector molecules of broiler.

Li S, Zhi L, Liu Y, Shen J, Liu L, Yao J, Yang X.

Br J Nutr. 2016 Feb 14;115(3):411-21. doi: 10.1017/S0007114515004511. Epub 2015 Nov 20.

PMID:
26586196
10.

High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism.

Aarabi M, San Gabriel MC, Chan D, Behan NA, Caron M, Pastinen T, Bourque G, MacFarlane AJ, Zini A, Trasler J.

Hum Mol Genet. 2015 Nov 15;24(22):6301-13. doi: 10.1093/hmg/ddv338. Epub 2015 Aug 24.

11.

Prenatal alcohol exposure alters methyl metabolism and programs serotonin transporter and glucocorticoid receptor expression in brain.

Ngai YF, Sulistyoningrum DC, O'Neill R, Innis SM, Weinberg J, Devlin AM.

Am J Physiol Regul Integr Comp Physiol. 2015 Sep;309(5):R613-22. doi: 10.1152/ajpregu.00075.2015. Epub 2015 Jul 15.

12.

Altered LINE-1 Methylation in Mothers of Children with Down Syndrome.

Božović IB, Stanković A, Živković M, Vraneković J, Kapović M, Brajenović-Milić B.

PLoS One. 2015 May 27;10(5):e0127423. doi: 10.1371/journal.pone.0127423. eCollection 2015.

13.

Effects of antiepileptic drug monotherapy on one-carbon metabolism and DNA methylation in patients with epilepsy.

Ni G, Qin J, Li H, Chen Z, Zhou Y, Fang Z, Chen Y, Zhou J, Huang M, Zhou L.

PLoS One. 2015 Apr 27;10(4):e0125656. doi: 10.1371/journal.pone.0125656. eCollection 2015.

14.

Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines.

Huemer M, Kožich V, Rinaldo P, Baumgartner MR, Merinero B, Pasquini E, Ribes A, Blom HJ.

J Inherit Metab Dis. 2015 Nov;38(6):1007-19. doi: 10.1007/s10545-015-9830-z. Epub 2015 Mar 12. Review.

15.

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.

Christensen KE, Mikael LG, Leung KY, Lévesque N, Deng L, Wu Q, Malysheva OV, Best A, Caudill MA, Greene ND, Rozen R.

Am J Clin Nutr. 2015 Mar;101(3):646-58. doi: 10.3945/ajcn.114.086603. Epub 2015 Jan 7.

16.

Emerging roles for folate and related B-vitamins in brain health across the lifecycle.

McGarel C, Pentieva K, Strain JJ, McNulty H.

Proc Nutr Soc. 2015 Feb;74(1):46-55. doi: 10.1017/S0029665114001554. Epub 2014 Nov 5. Review.

PMID:
25371067
17.

Heterozygote advantage of methylenetetrahydrofolate reductase polymorphisms on clinical outcomes in advanced non-small cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy.

Li X, Shao M, Wang S, Zhao X, Chen H, Qian J, Song X, Wang J, Jin L, Wu J, Li Q, Bai C, Han B, Gao Z, Lu D.

Tumour Biol. 2014 Nov;35(11):11159-70. doi: 10.1007/s13277-014-2427-6. Epub 2014 Aug 8.

PMID:
25104092
18.

Dietary B vitamin and methionine intake and MTHFR C677T genotype on risk of colorectal tumors in Lynch syndrome: the GEOLynch cohort study.

Jung AY, van Duijnhoven FJ, Nagengast FM, Botma A, Heine-Bröring RC, Kleibeuker JH, Vasen HF, Harryvan JL, Winkels RM, Kampman E.

Cancer Causes Control. 2014 Sep;25(9):1119-29. doi: 10.1007/s10552-014-0412-4. Epub 2014 Jun 12.

PMID:
24916333
19.

Long-term epigenetic effects of exposure to low doses of 56Fe in the mouse lung.

Nzabarushimana E, Miousse IR, Shao L, Chang J, Allen AR, Turner J, Stewart B, Raber J, Koturbash I.

J Radiat Res. 2014 Jul;55(4):823-8. doi: 10.1093/jrr/rru010. Epub 2014 Feb 28.

20.

Significance of dietary folate intake, homocysteine levels and MTHFR 677 C>T genotyping in South African patients diagnosed with depression: test development for clinical application.

Delport D, Schoeman R, van der Merwe N, van der Merwe L, Fisher LR, Geiger D, Kotze MJ.

Metab Brain Dis. 2014 Jun;29(2):377-84. doi: 10.1007/s11011-014-9506-7. Epub 2014 Feb 18.

PMID:
24532086

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