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Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology.

Rangan P, Choi I, Wei M, Navarrete G, Guen E, Brandhorst S, Enyati N, Pasia G, Maesincee D, Ocon V, Abdulridha M, Longo VD.

Cell Rep. 2019 Mar 5;26(10):2704-2719.e6. doi: 10.1016/j.celrep.2019.02.019.


Exploiting FAsting-mimicking Diet and MEtformin to Improve the Efficacy of Platinum-pemetrexed Chemotherapy in Advanced LKB1-inactivated Lung Adenocarcinoma: The FAME Trial.

Vernieri C, Signorelli D, Galli G, Ganzinelli M, Moro M, Fabbri A, Tamborini E, Marabese M, Caiola E, Broggini M, Hollander L, Gallucci R, Vandoni G, Gavazzi C, Triulzi T, Colombo MP, Rizzo AM, Corsetto PA, Pruneri G, de Braud F, Sozzi G, Torri V, Garassino MC.

Clin Lung Cancer. 2018 Dec 19. pii: S1525-7304(18)30335-8. doi: 10.1016/j.cllc.2018.12.011. [Epub ahead of print]


To fast, or not to fast before chemotherapy, that is the question.

Caccialanza R, Cereda E, De Lorenzo F, Farina G, Pedrazzoli P; AIOM-SINPE-FAVO Working Group.

BMC Cancer. 2018 Mar 27;18(1):337. doi: 10.1186/s12885-018-4245-5. Review.


Intermittent fasting and cardiovascular disease: current evidence and unresolved questions.

Tinsley GM, Horne BD.

Future Cardiol. 2018 Jan;14(1):47-54. doi: 10.2217/fca-2017-0038. Epub 2017 Dec 4. Review.


High dietary selenium intake is associated with less insulin resistance in the Newfoundland population.

Wang Y, Lin M, Gao X, Pedram P, Du J, Vikram C, Gulliver W, Zhang H, Sun G.

PLoS One. 2017 Apr 5;12(4):e0174149. doi: 10.1371/journal.pone.0174149. eCollection 2017.


Engineered Resistant-Starch (ERS) Diet Shapes Colon Microbiota Profile in Parallel with the Retardation of Tumor Growth in In Vitro and In Vivo Pancreatic Cancer Models.

Panebianco C, Adamberg K, Adamberg S, Saracino C, Jaagura M, Kolk K, Di Chio AG, Graziano P, Vilu R, Pazienza V.

Nutrients. 2017 Mar 27;9(4). pii: E331. doi: 10.3390/nu9040331.


Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease.

Wei M, Brandhorst S, Shelehchi M, Mirzaei H, Cheng CW, Budniak J, Groshen S, Mack WJ, Guen E, Di Biase S, Cohen P, Morgan TE, Dorff T, Hong K, Michalsen A, Laviano A, Longo VD.

Sci Transl Med. 2017 Feb 15;9(377). pii: eaai8700. doi: 10.1126/scitranslmed.aai8700.


Impact of intermittent fasting on health and disease processes.

Mattson MP, Longo VD, Harvie M.

Ageing Res Rev. 2017 Oct;39:46-58. doi: 10.1016/j.arr.2016.10.005. Epub 2016 Oct 31. Review.


Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity.

Di Biase S, Lee C, Brandhorst S, Manes B, Buono R, Cheng CW, Cacciottolo M, Martin-Montalvo A, de Cabo R, Wei M, Morgan TE, Longo VD.

Cancer Cell. 2016 Jul 11;30(1):136-146. doi: 10.1016/j.ccell.2016.06.005.


A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.

Choi IY, Piccio L, Childress P, Bollman B, Ghosh A, Brandhorst S, Suarez J, Michalsen A, Cross AH, Morgan TE, Wei M, Paul F, Bock M, Longo VD.

Cell Rep. 2016 Jun 7;15(10):2136-2146. doi: 10.1016/j.celrep.2016.05.009. Epub 2016 May 26.


Impact of Diet-Induced Obesity and Testosterone Deficiency on the Cardiovascular System: A Novel Rodent Model Representative of Males with Testosterone-Deficient Metabolic Syndrome (TDMetS).

Donner DG, Elliott GE, Beck BR, Bulmer AC, Du Toit EF.

PLoS One. 2015 Sep 14;10(9):e0138019. doi: 10.1371/journal.pone.0138019. eCollection 2015.


Interventions to Slow Aging in Humans: Are We Ready?

Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L.

Aging Cell. 2015 Aug;14(4):497-510. doi: 10.1111/acel.12338. Epub 2015 Apr 22. Review.


Central nervous insulin administration does not potentiate the acute glucoregulatory impact of concurrent mild hyperinsulinemia.

Ott V, Lehnert H, Staub J, Wönne K, Born J, Hallschmid M.

Diabetes. 2015 Mar;64(3):760-5. doi: 10.2337/db14-0931. Epub 2014 Oct 2.


Protein and amino acid restriction, aging and disease: from yeast to humans.

Mirzaei H, Suarez JA, Longo VD.

Trends Endocrinol Metab. 2014 Nov;25(11):558-66. doi: 10.1016/j.tem.2014.07.002. Epub 2014 Aug 19. Review.


[Protective effects of rhein on hepatic progression in HBV-transgenic mice with nonalcoholic steatohepatitis induced by a high-fat diet].

Bian DX, Liu J, Lu L, Liu H, Guo JC, Yang WJ, Liu YL, Luo Y, Zhuang ZJ, Chen JY, Shi JP, Xun YH.

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2013 Oct;27(5):328-31. Chinese.


A healthy diet with and without cereal grains and dairy products in patients with type 2 diabetes: study protocol for a random-order cross-over pilot study--Alimentation and Diabetes in Lanzarote--ADILAN.

Fontes-Villalba M, Jönsson T, Granfeldt Y, Frassetto LA, Sundquist J, Sundquist K, Carrera-Bastos P, Fika-Hernándo M, Picazo Ó, Lindeberg S.

Trials. 2014 Jan 2;15:2. doi: 10.1186/1745-6215-15-2.


Fasting enhances the response of glioma to chemo- and radiotherapy.

Safdie F, Brandhorst S, Wei M, Wang W, Lee C, Hwang S, Conti PS, Chen TC, Longo VD.

PLoS One. 2012;7(9):e44603. doi: 10.1371/journal.pone.0044603. Epub 2012 Sep 11.


Effect of tight glucose control with insulin on the thyroid axis of critically ill children and its relation with outcome.

Gielen M, Mesotten D, Wouters PJ, Desmet L, Vlasselaers D, Vanhorebeek I, Langouche L, Van den Berghe G.

J Clin Endocrinol Metab. 2012 Oct;97(10):3569-76. doi: 10.1210/jc.2012-2240. Epub 2012 Aug 7.


Overnight glucose infusion suppresses renal ammoniagenesis and reduces hyperammonaemia induced by a simulated bleed in cirrhotic patients.

Mpabanzi L, Deutz N, Hayes PC, Dejong CH, Olde Damink SW, Jalan R.

Aliment Pharmacol Ther. 2012 Apr;35(8):921-8. doi: 10.1111/j.1365-2036.2012.05044.x. Epub 2012 Feb 23.


Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats.

Conde SV, Nunes da Silva T, Gonzalez C, Mota Carmo M, Monteiro EC, Guarino MP.

Br J Nutr. 2012 Jan;107(1):86-95. doi: 10.1017/S0007114511002406. Epub 2011 Jun 23.


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