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Items: 1 to 20 of 53

1.

A new ex vivo human oral mucosa model reveals that p38MAPK inhibition is not effective in preventing autoantibody-induced mucosal blistering in pemphigus.

Egu DT, Sigmund AM, Schmidt E, Spindler V, Walter E, Waschke J.

Br J Dermatol. 2019 Jun 19. doi: 10.1111/bjd.18237. [Epub ahead of print]

PMID:
31218663
2.

Role of Src and Cortactin in Pemphigus Skin Blistering.

Kugelmann D, Rötzer V, Walter E, Egu DT, Fuchs MT, Vielmuth F, Vargas-Robles H, Schnoor M, Hertl M, Eming R, Rottner K, Schmidt A, Spindler V, Waschke J.

Front Immunol. 2019 Apr 4;10:626. doi: 10.3389/fimmu.2019.00626. eCollection 2019.

3.

Plakophilin 1 but not plakophilin 3 regulates desmoglein clustering.

Fuchs M, Foresti M, Radeva MY, Kugelmann D, Keil R, Hatzfeld M, Spindler V, Waschke J, Vielmuth F.

Cell Mol Life Sci. 2019 Sep;76(17):3465-3476. doi: 10.1007/s00018-019-03083-8. Epub 2019 Apr 4.

PMID:
30949721
4.

Desmoglein 1 Deficiency Causes Lethal Skin Blistering.

Kugelmann D, Radeva MY, Spindler V, Waschke J.

J Invest Dermatol. 2019 Jul;139(7):1596-1599.e2. doi: 10.1016/j.jid.2019.01.002. Epub 2019 Jan 17. No abstract available.

PMID:
30660666
5.

Premacular membranes in tissue culture.

Vogt D, Vielmuth F, Wertheimer C, Hagenau F, Guenther SR, Wolf A, Spindler V, Priglinger SG, Schumann RG.

Graefes Arch Clin Exp Ophthalmol. 2018 Sep;256(9):1589-1597. doi: 10.1007/s00417-018-4033-6. Epub 2018 Jun 21.

PMID:
29931427
6.

Keratin Retraction and Desmoglein3 Internalization Independently Contribute to Autoantibody-Induced Cell Dissociation in Pemphigus Vulgaris.

Schlögl E, Radeva MY, Vielmuth F, Schinner C, Waschke J, Spindler V.

Front Immunol. 2018 Apr 25;9:858. doi: 10.3389/fimmu.2018.00858. eCollection 2018.

7.

Atomic Force Microscopy Provides New Mechanistic Insights into the Pathogenesis of Pemphigus.

Vielmuth F, Spindler V, Waschke J.

Front Immunol. 2018 Mar 28;9:485. doi: 10.3389/fimmu.2018.00485. eCollection 2018. Review.

8.

Keratins Regulate p38MAPK-Dependent Desmoglein Binding Properties in Pemphigus.

Vielmuth F, Walter E, Fuchs M, Radeva MY, Buechau F, Magin TM, Spindler V, Waschke J.

Front Immunol. 2018 Mar 19;9:528. doi: 10.3389/fimmu.2018.00528. eCollection 2018.

9.

Pemphigus-A Disease of Desmosome Dysfunction Caused by Multiple Mechanisms.

Spindler V, Waschke J.

Front Immunol. 2018 Feb 1;9:136. doi: 10.3389/fimmu.2018.00136. eCollection 2018. Review.

10.

Mechanisms Causing Loss of Keratinocyte Cohesion in Pemphigus.

Spindler V, Eming R, Schmidt E, Amagai M, Grando S, Jonkman MF, Kowalczyk AP, Müller EJ, Payne AS, Pincelli C, Sinha AA, Sprecher E, Zillikens D, Hertl M, Waschke J.

J Invest Dermatol. 2018 Jan;138(1):32-37. doi: 10.1016/j.jid.2017.06.022. Epub 2017 Oct 14. Review.

11.

Keratins Regulate the Adhesive Properties of Desmosomal Cadherins through Signaling.

Vielmuth F, Wanuske MT, Radeva MY, Hiermaier M, Kugelmann D, Walter E, Buechau F, Magin TM, Waschke J, Spindler V.

J Invest Dermatol. 2018 Jan;138(1):121-131. doi: 10.1016/j.jid.2017.08.033. Epub 2017 Sep 9.

12.

Propiedades biomecánicas de la membrana limitante interna tras recibir tratamiento intravítreo con ocriplasmina.

Vielmuth F, Schumann RG, Spindler V, Wolf A, Scheler R, Mayer WJ, Henrich PB, Haritoglou C.

Ophthalmologica. 2017;238 Suppl 1:1-8. doi: 10.1159/000477510. Epub 2017 Jul 11. Spanish.

13.

Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus.

Walter E, Vielmuth F, Rotkopf L, Sárdy M, Horváth ON, Goebeler M, Schmidt E, Eming R, Hertl M, Spindler V, Waschke J.

Sci Rep. 2017 Jun 15;7(1):3579. doi: 10.1038/s41598-017-03697-7.

14.

Inhibition of p38MAPK signalling prevents epidermal blistering and alterations of desmosome structure induced by pemphigus autoantibodies in human epidermis.

Egu DT, Walter E, Spindler V, Waschke J.

Br J Dermatol. 2017 Dec;177(6):1612-1618. doi: 10.1111/bjd.15721. Epub 2017 Nov 14.

PMID:
28600798
15.

Meeting Report of the Pathogenesis of Pemphigus and Pemphigoid Meeting in Munich, September 2016.

Schmidt E, Spindler V, Eming R, Amagai M, Antonicelli F, Baines JF, Belheouane M, Bernard P, Borradori L, Caproni M, Di Zenzo G, Grando S, Harman K, Jonkman MF, Koga H, Ludwig RJ, Kowalczyk AP, Müller EJ, Nishie W, Pas H, Payne AS, Sadik CD, Seppänen A, Setterfield J, Shimizu H, Sinha AA, Sprecher E, Sticherling M, Ujiie H, Zillikens D, Hertl M, Waschke J.

J Invest Dermatol. 2017 Jun;137(6):1199-1203. doi: 10.1016/j.jid.2017.01.028. Epub 2017 Apr 5. Review.

16.

Adrenergic Signaling Strengthens Cardiac Myocyte Cohesion.

Schinner C, Vielmuth F, Rötzer V, Hiermaier M, Radeva MY, Co TK, Hartlieb E, Schmidt A, Imhof A, Messoudi A, Horn A, Schlipp A, Spindler V, Waschke J.

Circ Res. 2017 Apr 14;120(8):1305-1317. doi: 10.1161/CIRCRESAHA.116.309631. Epub 2017 Mar 13.

PMID:
28289018
17.

Loss of desmoglein 2 promotes tumorigenic behavior in pancreatic cancer cells.

Hütz K, Zeiler J, Sachs L, Ormanns S, Spindler V.

Mol Carcinog. 2017 Aug;56(8):1884-1895. doi: 10.1002/mc.22644. Epub 2017 Mar 30.

PMID:
28277619
18.

Pemphigus Autoantibodies Induce Blistering in Human Conjunctiva.

Vielmuth F, Rötzer V, Hartlieb E, Hirneiß C, Waschke J, Spindler V.

Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4442-4449. doi: 10.1167/iovs.16-19582.

PMID:
27750289
19.

Biomechanical Properties of the Internal Limiting Membrane after Intravitreal Ocriplasmin Treatment.

Vielmuth F, Schumann RG, Spindler V, Wolf A, Scheler R, Mayer WJ, Henrich PB, Haritoglou C.

Ophthalmologica. 2016;235(4):233-40. doi: 10.1159/000444508. Epub 2016 Apr 28.

PMID:
27120551
20.

Desmoglein 3-Dependent Signaling Regulates Keratinocyte Migration and Wound Healing.

Rötzer V, Hartlieb E, Winkler J, Walter E, Schlipp A, Sardy M, Spindler V, Waschke J.

J Invest Dermatol. 2016 Jan;136(1):301-10. doi: 10.1038/JID.2015.380.

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