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Items: 1 to 20 of 36


A cell fitness selection model for neuronal survival during development.

Wang Y, Wu H, Fontanet P, Codeluppi S, Akkuratova N, Petitpré C, Xue-Franzén Y, Niederreither K, Sharma A, Da Silva F, Comai G, Agirman G, Palumberi D, Linnarsson S, Adameyko I, Moqrich A, Schedl A, La Manno G, Hadjab S, Lallemend F.

Nat Commun. 2019 Sep 12;10(1):4137. doi: 10.1038/s41467-019-12119-3.


The Adult Adrenal Cortex Undergoes Rapid Tissue Renewal in a Sex-Specific Manner.

Grabek A, Dolfi B, Klein B, Jian-Motamedi F, Chaboissier MC, Schedl A.

Cell Stem Cell. 2019 Aug 1;25(2):290-296.e2. doi: 10.1016/j.stem.2019.04.012. Epub 2019 May 16.


Awakening the Bowman: inhibition of CXCL12 signaling activates parietal epithelial cells.

Massa F, Schedl A.

Kidney Int. 2018 Dec;94(6):1042-1044. doi: 10.1016/j.kint.2018.09.011.


The author replies.

Schedl A.

Kidney Int. 2018 Oct;94(4):827. doi: 10.1016/j.kint.2018.06.015. No abstract available.


Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4.

Da Silva F, Massa F, Motamedi FJ, Vidal V, Rocha AS, Gregoire EP, Cai CL, Wagner KD, Schedl A.

Dev Biol. 2018 Sep 1;441(1):42-51. doi: 10.1016/j.ydbio.2018.05.024. Epub 2018 May 31.


Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).

Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A.

Kidney Int. 2018 May;93(5):1142-1153. doi: 10.1016/j.kint.2017.11.026. Epub 2018 Feb 17.


Genetic and Molecular Insights Into Genotype-Phenotype Relationships in Osteopathia Striata With Cranial Sclerosis (OSCS) Through the Analysis of Novel Mouse Wtx Mutant Alleles.

Comai G, Boutet A, Tanneberger K, Massa F, Rocha AS, Charlet A, Panzolini C, Jian Motamedi F, Brommage R, Hans W, Funck-Brentano T, Hrabe de Angelis M, Hartmann C, Cohen-Solal M, Behrens J, Schedl A.

J Bone Miner Res. 2018 May;33(5):875-887. doi: 10.1002/jbmr.3387. Epub 2018 Mar 1.


Coronary Artery Formation Is Driven by Localized Expression of R-spondin3.

Da Silva F, Rocha AS, Motamedi FJ, Massa F, Basboga C, Morrison H, Wagner KD, Schedl A.

Cell Rep. 2017 Aug 22;20(8):1745-1754. doi: 10.1016/j.celrep.2017.08.004.


Repression of CMIP transcription by WT1 is relevant to podocyte health.

Moktefi A, Zhang SY, Vachin P, Ory V, Henique C, Audard V, Rucker-Martin C, Gouadon E, Eccles M, Schedl A, Heidet L, Ollero M, Sahali D, Pawlak A.

Kidney Int. 2016 Dec;90(6):1298-1311. doi: 10.1016/j.kint.2016.07.016. Epub 2016 Sep 17.


PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development.

Drelon C, Berthon A, Sahut-Barnola I, Mathieu M, Dumontet T, Rodriguez S, Batisse-Lignier M, Tabbal H, Tauveron I, Lefrançois-Martinez AM, Pointud JC, Gomez-Sanchez CE, Vainio S, Shan J, Sacco S, Schedl A, Stratakis CA, Martinez A, Val P.

Nat Commun. 2016 Sep 14;7:12751. doi: 10.1038/ncomms12751.


Identifying Direct Downstream Targets: WT1 ChIP-Seq Analysis.

da Silva F, Massa F, Schedl A.

Methods Mol Biol. 2016;1467:177-88. doi: 10.1007/978-1-4939-4023-3_15.


The adrenal capsule is a signaling center controlling cell renewal and zonation through Rspo3.

Vidal V, Sacco S, Rocha AS, da Silva F, Panzolini C, Dumontet T, Doan TM, Shan J, Rak-Raszewska A, Bird T, Vainio S, Martinez A, Schedl A.

Genes Dev. 2016 Jun 15;30(12):1389-94. doi: 10.1101/gad.277756.116. Epub 2016 Jun 16.


The Angiocrine Factor Rspondin3 Is a Key Determinant of Liver Zonation.

Rocha AS, Vidal V, Mertz M, Kendall TJ, Charlet A, Okamoto H, Schedl A.

Cell Rep. 2015 Dec 1;13(9):1757-64. doi: 10.1016/j.celrep.2015.10.049. Epub 2015 Nov 19.


Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney.

Kumar S, Liu J, Pang P, Krautzberger AM, Reginensi A, Akiyama H, Schedl A, Humphreys BD, McMahon AP.

Cell Rep. 2015 Aug 25;12(8):1325-38. doi: 10.1016/j.celrep.2015.07.034. Epub 2015 Aug 13.


Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.

Lefebvre J, Clarkson M, Massa F, Bradford ST, Charlet A, Buske F, Lacas-Gervais S, Schulz H, Gimpel C, Hata Y, Schaefer F, Schedl A.

Kidney Int. 2015 Aug;88(2):321-31. doi: 10.1038/ki.2015.140. Epub 2015 May 20.


Steroidogenic organ development and homeostasis: A WT1-centric view.

Bandiera R, Sacco S, Vidal VP, Chaboissier MC, Schedl A.

Mol Cell Endocrinol. 2015 Jun 15;408:145-55. doi: 10.1016/j.mce.2015.01.009. Epub 2015 Jan 14. Review.


WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors.

Motamedi FJ, Badro DA, Clarkson M, Lecca MR, Bradford ST, Buske FA, Saar K, Hübner N, Brändli AW, Schedl A.

Nat Commun. 2014 Jul 17;5:4444. doi: 10.1038/ncomms5444.


Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source.

Chau YY, Bandiera R, Serrels A, Martínez-Estrada OM, Qing W, Lee M, Slight J, Thornburn A, Berry R, McHaffie S, Stimson RH, Walker BR, Chapuli RM, Schedl A, Hastie N.

Nat Cell Biol. 2014 Apr;16(4):367-75. doi: 10.1038/ncb2922. Epub 2014 Mar 9.


WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland.

Bandiera R, Vidal VP, Motamedi FJ, Clarkson M, Sahut-Barnola I, von Gise A, Pu WT, Hohenstein P, Martinez A, Schedl A.

Dev Cell. 2013 Oct 14;27(1):5-18. doi: 10.1016/j.devcel.2013.09.003.


Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals.

Lavery R, Chassot AA, Pauper E, Gregoire EP, Klopfenstein M, de Rooij DG, Mark M, Schedl A, Ghyselinck NB, Chaboissier MC.

PLoS Genet. 2012;8(12):e1003170. doi: 10.1371/journal.pgen.1003170. Epub 2012 Dec 27.

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