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Items: 1 to 20 of 33

1.

Protein tyrosine phosphatases in cardiac physiology and pathophysiology.

Wade F, Belhaj K, Poizat C.

Heart Fail Rev. 2018 Mar;23(2):261-272. doi: 10.1007/s10741-018-9676-1. Review.

2.

Rosiglitazone promotes cardiac hypertrophy and alters chromatin remodeling in isolated cardiomyocytes.

Pharaon LF, El-Orabi NF, Kunhi M, Al Yacoub N, Awad SM, Poizat C.

Toxicol Lett. 2017 Oct 5;280:151-158. doi: 10.1016/j.toxlet.2017.08.011. Epub 2017 Aug 16.

PMID:
28822817
3.

Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-╬▓1/Smad and GRAP pathways.

Al-Onazi AS, Al-Rasheed NM, Attia HA, Al-Rasheed NM, Ahmed RM, Al-Amin MA, Poizat C.

J Pharm Pharmacol. 2016 Feb;68(2):219-32. doi: 10.1111/jphp.12504. Epub 2016 Jan 28.

PMID:
26817709
4.

FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy.

Al-Yacoub N, Shaheen R, Awad SM, Kunhi M, Dzimiri N, Nguyen HC, Xiong Y, Al-Buraiki J, Al-Habeeb W, Alkuraya FS, Poizat C.

Genome Biol. 2016 Jan 11;17:2. doi: 10.1186/s13059-015-0861-4.

5.

TLE6 mutation causes the earliest known human embryonic lethality.

Alazami AM, Awad SM, Coskun S, Al-Hassan S, Hijazi H, Abdulwahab FM, Poizat C, Alkuraya FS.

Genome Biol. 2015 Nov 5;16:240. doi: 10.1186/s13059-015-0792-0.

6.

Nuclear Calcium/Calmodulin-dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage Commitment.

Quijada P, Hariharan N, Cubillo JD, Bala KM, Emathinger JM, Wang BJ, Ormachea L, Bers DM, Sussman MA, Poizat C.

J Biol Chem. 2015 Oct 16;290(42):25411-26. doi: 10.1074/jbc.M115.657775. Epub 2015 Aug 31.

7.

Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress-induced cardiomyopathy.

Wade F, Quijada P, Al-Haffar KM, Awad SM, Kunhi M, Toko H, Marashly Q, Belhaj K, Zahid I, Al-Mohanna F, Stanford SM, Alvarez R, Liu Y, Colak D, Jordan MC, Roos KP, Assiri A, Al-Habeeb W, Sussman M, Bottini N, Poizat C.

J Pathol. 2015 Dec;237(4):482-94. doi: 10.1002/path.4594. Epub 2015 Sep 1.

8.

Recessive mutations in COL25A1 are a cause of congenital cranial dysinnervation disorder.

Shinwari JM, Khan A, Awad S, Shinwari Z, Alaiya A, Alanazi M, Tahir A, Poizat C, Al Tassan N.

Am J Hum Genet. 2015 Jan 8;96(1):147-52. doi: 10.1016/j.ajhg.2014.11.006. Epub 2014 Dec 11.

9.

Control of histone H3 phosphorylation by CaMKII╬┤ in response to haemodynamic cardiac stress.

Awad S, Al-Haffar KM, Marashly Q, Quijada P, Kunhi M, Al-Yacoub N, Wade FS, Mohammed SF, Al-Dayel F, Sutherland G, Assiri A, Sussman M, Bers D, Al-Habeeb W, Poizat C.

J Pathol. 2015 Mar;235(4):606-18. doi: 10.1002/path.4489. Epub 2014 Dec 17.

10.

Cardiac SERCA2A/B: therapeutic targets for heart failure.

Shareef MA, Anwer LA, Poizat C.

Eur J Pharmacol. 2014 Feb 5;724:1-8. doi: 10.1016/j.ejphar.2013.12.018. Epub 2013 Dec 18. Review.

PMID:
24361307
11.

Mutations in CSPP1, encoding a core centrosomal protein, cause a range of ciliopathy phenotypes in humans.

Shaheen R, Shamseldin HE, Loucks CM, Seidahmed MZ, Ansari S, Ibrahim Khalil M, Al-Yacoub N, Davis EE, Mola NA, Szymanska K, Herridge W, Chudley AE, Chodirker BN, Schwartzentruber J, Majewski J, Katsanis N, Poizat C, Johnson CA, Parboosingh J, Boycott KM, Innes AM, Alkuraya FS.

Am J Hum Genet. 2014 Jan 2;94(1):73-9. doi: 10.1016/j.ajhg.2013.11.010. Epub 2013 Dec 19.

12.

Epigenetics and chromatin remodeling in adult cardiomyopathy.

Mahmoud SA, Poizat C.

J Pathol. 2013 Oct;231(2):147-57. doi: 10.1002/path.4234. Review.

13.

Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy.

Awad S, Kunhi M, Little GH, Bai Y, An W, Bers D, Kedes L, Poizat C.

Nucleic Acids Res. 2013 Sep;41(16):7656-72. doi: 10.1093/nar/gkt500. Epub 2013 Jun 26.

14.

Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis.

Awad S, Al-Dosari MS, Al-Yacoub N, Colak D, Salih MA, Alkuraya FS, Poizat C.

Hum Mol Genet. 2013 Jun 1;22(11):2200-13. doi: 10.1093/hmg/ddt072. Epub 2013 Feb 14.

PMID:
23418308
15.

An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis.

Innocenzi A, Latella L, Messina G, Simonatto M, Marullo F, Berghella L, Poizat C, Shu CW, Wang JY, Puri PL, Cossu G.

EMBO Rep. 2011 Feb;12(2):164-71. doi: 10.1038/embor.2010.195. Epub 2011 Jan 7.

16.

Critical role of nuclear calcium/calmodulin-dependent protein kinase IIdeltaB in cardiomyocyte survival in cardiomyopathy.

Little GH, Saw A, Bai Y, Dow J, Marjoram P, Simkhovich B, Leeka J, Kedes L, Kloner RA, Poizat C.

J Biol Chem. 2009 Sep 11;284(37):24857-68. doi: 10.1074/jbc.M109.003186. Epub 2009 Jul 14.

17.

Nuclear calcium/calmodulin-dependent protein kinase IIdelta preferentially transmits signals to histone deacetylase 4 in cardiac cells.

Little GH, Bai Y, Williams T, Poizat C.

J Biol Chem. 2007 Mar 9;282(10):7219-31. Epub 2006 Dec 19.

18.

In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4.

Mao C, Tai WC, Bai Y, Poizat C, Lee AS.

J Biol Chem. 2006 Mar 31;281(13):8877-87. Epub 2006 Feb 1.

19.
20.

New cellular and molecular approaches for the treatment of cardiac disease.

Kedes L, Kloner R, Kong K, Poizat C, Simkhovich B, Iso T, Hamamori Y.

Semin Nephrol. 2004 Sep;24(5):437-40. Review.

PMID:
15490406

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