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Items: 1 to 20 of 402


ABCA7 loss-of-function variants, expression, and neurologic disease risk.

Allen M, Lincoln SJ, Corda M, Watzlawik JO, Carrasquillo MM, Reddy JS, Burgess JD, Nguyen T, Malphrus K, Petersen RC, Graff-Radford NR, Dickson DW, Ertekin-Taner N.

Neurol Genet. 2017 Jan 5;3(1):e126. doi: 10.1212/NXG.0000000000000126.


Excessive daytime sleepiness and fatigue may indicate accelerated brain aging in cognitively normal late middle-aged and older adults.

Carvalho DZ, St Louis EK, Boeve BF, Mielke MM, Przybelski SA, Knopman DS, Machulda MM, Roberts RO, Geda YE, Petersen RC, Jack CR Jr, Vemuri P.

Sleep Med. 2016 Nov 3. pii: S1389-9457(16)30225-8. doi: 10.1016/j.sleep.2016.08.023. [Epub ahead of print]


A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity.

Schwarz CG, Gunter JL, Wiste HJ, Przybelski SA, Weigand SD, Ward CP, Senjem ML, Vemuri P, Murray ME, Dickson DW, Parisi JE, Kantarci K, Weiner MW, Petersen RC, Jack CR Jr; Alzheimer's Disease Neuroimaging Initiative..

Neuroimage Clin. 2016 May 30;11:802-812. doi: 10.1016/j.nicl.2016.05.017.


Brain tau deposition linked to systemic causes of death in normal elderly.

Josephs KA, Tosakulwong N, Weigand SD, Murray ME, Whitwell JL, Parisi JE, Dickson DW, Petersen RC.

Neurobiol Aging. 2017 Feb;50:163-166. doi: 10.1016/j.neurobiolaging.2016.11.011.


First PET Imaging Studies With 63Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease.

DeGrado TR, Kemp BJ, Pandey MK, Jiang H, Gunderson TM, Linscheid LR, Woodwick AR, McConnell DM, Fletcher JG, Johnson GB, Petersen RC, Knopman DS, Lowe VJ.

Mol Imaging. 2016 Dec 9;15. pii: 1536012116673793.


A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.

Carrasquillo MM, Allen M, Burgess JD, Wang X, Strickland SL, Aryal S, Siuda J, Kachadoorian ML, Medway C, Younkin CS, Nair A, Wang C, Chanana P, Serie D, Nguyen T, Lincoln S, Malphrus KG, Morgan K, Golde TE, Price ND, White CC, De Jager PL, Bennett DA, Asmann YW, Crook JE, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N.

Alzheimers Dement. 2016 Dec 8. pii: S1552-5260(16)33071-0. doi: 10.1016/j.jalz.2016.10.005. [Epub ahead of print]


Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.

Chapuis J, Flaig A, Grenier-Boley B, Eysert F, Pottiez V, Deloison G, Vandeputte A, Ayral AM, Mendes T, Desai S, Goate AM, Kauwe JS, Leroux F, Herledan A, Demiautte F, Bauer C, Checler F, Petersen RC, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Albert M, Moghekar A, O'Brien R, Peskind ER, Malmanche N, Schellenberg GD, Dourlen P, Song OR, Cruchaga C, Amouyel P, Deprez B, Brodin P, Lambert JC; ADGC, Alzheimer’s Disease Neuroimaging Initiative..

Acta Neuropathol. 2016 Dec 8. [Epub ahead of print]


The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement.

Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR Jr, Jagust W, Morris JC, Petersen RC, Salazar J, Saykin AJ, Shaw LM, Toga AW, Trojanowski JQ; Alzheimer's Disease Neuroimaging Initiative..

Alzheimers Dement. 2016 Dec 5. pii: S1552-5260(16)33072-2. doi: 10.1016/j.jalz.2016.10.006. [Epub ahead of print] Review.


Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging.

Wennberg AM, Savica R, Hagen CE, Roberts RO, Knopman DS, Hollman JH, Vemuri P, Jack CR Jr, Petersen RC, Mielke MM.

J Am Geriatr Soc. 2016 Nov 21. doi: 10.1111/jgs.14670. [Epub ahead of print]


AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies.

Kantarci K, Lowe VJ, Boeve BF, Senjem ML, Tosakulwong N, Lesnick TG, Spychalla AJ, Gunter JL, Fields JA, Graff-Radford J, Ferman TJ, Jones DT, Murray ME, Knopman DS, Jack CR Jr, Petersen RC.

Ann Neurol. 2016 Nov 18. doi: 10.1002/ana.24825. [Epub ahead of print]


Clinicopathologic heterogeneity in FTDP-17 due to MAPT p.P301L mutation, including a patient with globular glial tauopathy.

Tacik P, Sanchez-Contreras M, DeTure M, Murray ME, Rademakers R, Ross OA, Wszolek ZK, Parisi JE, Knopman DS, Petersen RC, Dickson DW.

Neuropathol Appl Neurobiol. 2016 Nov 8. doi: 10.1111/nan.12367. [Epub ahead of print]


Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment.

Kantarci K, Lesnick T, Ferman TJ, Przybelski SA, Boeve BF, Smith GE, Kremers WK, Knopman DS, Jack CR Jr, Petersen RC.

Neurology. 2016 Nov 29;87(22):2317-2323.


Timing of Physical Activity, Apolipoprotein E ε4 Genotype, and Risk of Incident Mild Cognitive Impairment.

Krell-Roesch J, Pink A, Roberts RO, Stokin GB, Mielke MM, Spangehl KA, Bartley MM, Knopman DS, Christianson TJ, Petersen RC, Geda YE.

J Am Geriatr Soc. 2016 Dec;64(12):2479-2486. doi: 10.1111/jgs.14402.


Defining imaging biomarker cut points for brain aging and Alzheimer's disease.

Jack CR Jr, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Gunter JL, Senjem ML, Jones DT, Kantarci K, Machulda MM, Mielke MM, Roberts RO, Vemuri P, Reyes DA, Petersen RC.

Alzheimers Dement. 2016 Sep 30. pii: S1552-5260(16)32875-8. doi: 10.1016/j.jalz.2016.08.005. [Epub ahead of print]


[18 F]AV-1451 tau positron emission tomography in progressive supranuclear palsy.

Whitwell JL, Lowe VJ, Tosakulwong N, Weigand SD, Senjem ML, Schwarz CG, Spychalla AJ, Petersen RC, Jack CR Jr, Josephs KA.

Mov Disord. 2016 Oct 27. doi: 10.1002/mds.26834. [Epub ahead of print]


Tracking the development of agrammatic aphasia: A tensor-based morphometry study.

Whitwell JL, Duffy JR, Machulda MM, Clark HM, Strand EA, Senjem ML, Gunter JL, Spychalla AJ, Petersen RC, Jack CR Jr, Josephs KA.

Cortex. 2016 Sep 30. pii: S0010-9452(16)30264-7. doi: 10.1016/j.cortex.2016.09.017. [Epub ahead of print]


Optimizing PiB-PET SUVR change-over-time measurement by a large-scale analysis of longitudinal reliability, plausibility, separability, and correlation with MMSE.

Schwarz CG, Senjem ML, Gunter JL, Tosakulwong N, Weigand SD, Kemp BJ, Spychalla AJ, Vemuri P, Petersen RC, Lowe VJ, Jack CR Jr.

Neuroimage. 2017 Jan 1;144(Pt A):113-127. doi: 10.1016/j.neuroimage.2016.08.056.


Mild Cognitive Impairment and Risk of Critical Illness.

Teeters DA, Moua T, Li G, Kashyap R, Biehl M, Kaur R, Gajic O, Boeve BF, St Louis EK, Petersen RC, Caples SM.

Crit Care Med. 2016 Nov;44(11):2045-2051.


Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases.

Allen M, Carrasquillo MM, Funk C, Heavner BD, Zou F, Younkin CS, Burgess JD, Chai HS, Crook J, Eddy JA, Li H, Logsdon B, Peters MA, Dang KK, Wang X, Serie D, Wang C, Nguyen T, Lincoln S, Malphrus K, Bisceglio G, Li M, Golde TE, Mangravite LM, Asmann Y, Price ND, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N.

Sci Data. 2016 Oct 11;3:160089. doi: 10.1038/sdata.2016.89.


[Formula: see text]Practice effects and longitudinal cognitive change in clinically normal older adults differ by Alzheimer imaging biomarker status.

Machulda MM, Hagen CE, Wiste HJ, Mielke MM, Knopman DS, Roberts RO, Vemuri P, Lowe VJ, Jack CR Jr, Petersen RC.

Clin Neuropsychol. 2017 Jan;31(1):99-117. doi: 10.1080/13854046.2016.1241303.

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