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Items: 1 to 20 of 126

1.

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells.

Yang K, Blanco DB, Chen X, Dash P, Neale G, Rosencrance C, Easton J, Chen W, Cheng C, Dhungana Y, Kc A, Awad W, Guo XJ, Thomas PG, Chi H.

Sci Immunol. 2018 Jul 6;3(25). pii: eaas9818. doi: 10.1126/sciimmunol.aas9818.

PMID:
29980617
2.

Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells.

Du X, Wen J, Wang Y, Karmaus PWF, Khatamian A, Tan H, Li Y, Guy C, Nguyen TM, Dhungana Y, Neale G, Peng J, Yu J, Chi H.

Nature. 2018 Jun;558(7708):141-145. doi: 10.1038/s41586-018-0177-0. Epub 2018 May 30.

PMID:
29849151
3.

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis.

Chapman NM, Zeng H, Nguyen TM, Wang Y, Vogel P, Dhungana Y, Liu X, Neale G, Locasale JW, Chi H.

Nat Commun. 2018 May 29;9(1):2095. doi: 10.1038/s41467-018-04392-5.

4.

IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.

Karki R, Lee E, Place D, Samir P, Mavuluri J, Sharma BR, Balakrishnan A, Malireddi RKS, Geiger R, Zhu Q, Neale G, Kanneganti TD.

Cell. 2018 May 3;173(4):920-933.e13. doi: 10.1016/j.cell.2018.02.055. Epub 2018 Mar 22.

PMID:
29576451
5.

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, Dhungana Y, Guy C, Neale G, Cloer C, Peng J, Wang D, Chi H.

Sci Adv. 2018 Jan 31;4(1):eaar5701. doi: 10.1126/sciadv.aar5701. eCollection 2018 Jan.

6.

IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection.

Kuriakose T, Zheng M, Neale G, Kanneganti TD.

J Immunol. 2018 Feb 15;200(4):1489-1495. doi: 10.4049/jimmunol.1701538. Epub 2018 Jan 10.

PMID:
29321274
7.

PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.

Yu M, Chen Y, Zeng H, Zheng Y, Fu G, Zhu W, Broeckel U, Aggarwal P, Turner A, Neale G, Guy C, Zhu N, Chi H, Wen R, Wang D.

Nat Commun. 2017 Nov 13;8(1):1457. doi: 10.1038/s41467-017-01388-5.

8.

An Eye Organoid Approach Identifies Six3 Suppression of R-spondin 2 as a Critical Step in Mouse Neuroretina Differentiation.

Takata N, Abbey D, Fiore L, Acosta S, Feng R, Gil HJ, Lavado A, Geng X, Interiano A, Neale G, Eiraku M, Sasai Y, Oliver G.

Cell Rep. 2017 Nov 7;21(6):1534-1549. doi: 10.1016/j.celrep.2017.10.041.

9.

Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer.

Morton LM, Sampson JN, Armstrong GT, Chen TH, Hudson MM, Karlins E, Dagnall CL, Li SA, Wilson CL, Srivastava DK, Liu W, Kang G, Oeffinger KC, Henderson TO, Moskowitz CS, Gibson TM, Merino DM, Wong JR, Hammond S, Neglia JP, Turcotte LM, Miller J, Bowen L, Wheeler WA, Leisenring WM, Whitton JA, Burdette L, Chung C, Hicks BD, Jones K, Machiela MJ, Vogt A, Wang Z, Yeager M, Neale G, Lear M, Strong LC, Yasui Y, Stovall M, Weathers RE, Smith SA, Howell R, Davies SM, Radloff GA, Onel K, Berrington de González A, Inskip PD, Rajaraman P, Fraumeni JF Jr, Bhatia S, Chanock SJ, Tucker MA, Robison LL.

J Natl Cancer Inst. 2017 Nov 1;109(11). doi: 10.1093/jnci/djx058.

PMID:
29059430
10.

Identification of Clinical and Biologic Correlates Associated With Outcome in Children With Adrenocortical Tumors Without Germline TP53 Mutations: A St Jude Adrenocortical Tumor Registry and Children's Oncology Group Study.

Pinto EM, Rodriguez-Galindo C, Pounds SB, Wang L, Clay MR, Neale G, Garfinkle EAR, Lam CG, Levy CF, Pappo AS, Zambetti GP, Ribeiro RC.

J Clin Oncol. 2017 Dec 10;35(35):3956-3963. doi: 10.1200/JCO.2017.74.2460. Epub 2017 Oct 23.

PMID:
29058986
11.

Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling.

Yang K, Blanco DB, Neale G, Vogel P, Avila J, Clish CB, Wu C, Shrestha S, Rankin S, Long L, Kc A, Chi H.

Nature. 2017 Aug 31;548(7669):602-606. doi: 10.1038/nature23665. Epub 2017 Aug 23.

12.

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

Karmaus PWF, Herrada AA, Guy C, Neale G, Dhungana Y, Long L, Vogel P, Avila J, Clish CB, Chi H.

J Exp Med. 2017 Sep 4;214(9):2629-2647. doi: 10.1084/jem.20161855. Epub 2017 Aug 7.

13.

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.

Kuriakose T, Man SM, Subbarao Malireddi RK, Karki R, Kesavardhana S, Place DE, Neale G, Vogel P, Kanneganti TD.

Sci Immunol. 2016 Aug 12;1(2):aag2045. doi: 10.1126/sciimmunol.aag2045. Epub 2016 Aug 12.

PMID:
28783694
14.

Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis.

Fukuda Y, Wang Y, Lian S, Lynch J, Nagai S, Fanshawe B, Kandilci A, Janke LJ, Neale G, Fan Y, Sorrentino BP, Roussel MF, Grosveld G, Schuetz JD.

JCI Insight. 2017 Aug 3;2(15). pii: 92409. doi: 10.1172/jci.insight.92409. [Epub ahead of print]

15.

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.

Ghoneim HE, Fan Y, Moustaki A, Abdelsamed HA, Dash P, Dogra P, Carter R, Awad W, Neale G, Thomas PG, Youngblood B.

Cell. 2017 Jun 29;170(1):142-157.e19. doi: 10.1016/j.cell.2017.06.007. Epub 2017 Jun 22.

16.

Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes.

Shi LZ, Saravia J, Zeng H, Kalupahana NS, Guy CS, Neale G, Chi H.

Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E67-E74. doi: 10.1073/pnas.1617669114. Epub 2016 Dec 19.

17.

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.

Kuriakose T, Man SM, Malireddi RK, Karki R, Kesavardhana S, Place DE, Neale G, Vogel P, Kanneganti TD.

Sci Immunol. 2016 Aug 5;1(2). pii: aag2045. Epub 2016 Aug 12.

18.

T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions.

Van de Velde LA, Subramanian C, Smith AM, Barron L, Qualls JE, Neale G, Alfonso-Pecchio A, Jackowski S, Rock CO, Wynn TA, Murray PJ.

J Biol Chem. 2017 Jan 6;292(1):15-30. doi: 10.1074/jbc.M116.766238. Epub 2016 Nov 30.

19.

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RKS, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD.

Cell. 2016 Oct 6;167(2):382-396.e17. doi: 10.1016/j.cell.2016.09.012. Epub 2016 Sep 29.

20.

Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy.

Kamei A, Gao G, Neale G, Loh LN, Vogel P, Thomas PG, Tuomanen EI, Murray PJ.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6153-E6161. Epub 2016 Sep 26.

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