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Items: 1 to 20 of 146


Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution.

Heng JS, Rattner A, Stein-O'Brien GL, Winer BL, Jones BW, Vernon HJ, Goff LA, Nathans J.

Proc Natl Acad Sci U S A. 2019 Apr 15. pii: 201821122. doi: 10.1073/pnas.1821122116. [Epub ahead of print]


Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures.

Wang Y, Sabbagh MF, Gu X, Rattner A, Williams J, Nathans J.

Elife. 2019 Apr 1;8. pii: e43257. doi: 10.7554/eLife.43257.


Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood-brain barrier and blood-retina barrier development and maintenance.

Wang Y, Cho C, Williams J, Smallwood PM, Zhang C, Junge HJ, Nathans J.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11827-E11836. doi: 10.1073/pnas.1813217115. Epub 2018 Nov 26. Erratum in: Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3934.


Affinity capture of polyribosomes followed by RNAseq (ACAPseq), a discovery platform for protein-protein interactions.

Peng X, Emiliani F, Smallwood PM, Rattner A, Lei H, Sabbagh MF, Nathans J.

Elife. 2018 Oct 22;7. pii: e40982. doi: 10.7554/eLife.40982.


Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells.

Sabbagh MF, Heng JS, Luo C, Castanon RG, Nery JR, Rattner A, Goff LA, Ecker JR, Nathans J.

Elife. 2018 Sep 6;7. pii: e36187. doi: 10.7554/eLife.36187.


Peropsin modulates transit of vitamin A from retina to retinal pigment epithelium.

Cook JD, Ng SY, Lloyd M, Eddington S, Sun H, Nathans J, Bok D, Radu RA, Travis GH.

J Biol Chem. 2017 Dec 29;292(52):21407-21416. doi: 10.1074/jbc.M117.812701. Epub 2017 Nov 6.


Cerebral Vein Malformations Result from Loss of Twist1 Expression and BMP Signaling from Skull Progenitor Cells and Dura.

Tischfield MA, Robson CD, Gilette NM, Chim SM, Sofela FA, DeLisle MM, Gelber A, Barry BJ, MacKinnon S, Dagi LR, Nathans J, Engle EC.

Dev Cell. 2017 Sep 11;42(5):445-461.e5. doi: 10.1016/j.devcel.2017.07.027. Epub 2017 Aug 30.


Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation.

Cho C, Smallwood PM, Nathans J.

Neuron. 2017 Aug 30;95(5):1056-1073.e5. doi: 10.1016/j.neuron.2017.07.031. Epub 2017 Aug 10.


Population growth: Help to make food go further in Egypt.

Nathans J.

Nature. 2017 Jun 7;546(7657):210. doi: 10.1038/546210e. No abstract available.


Intramembrane Proteolysis of Astrotactins.

Chang H, Smallwood PM, Williams J, Nathans J.

J Biol Chem. 2017 Feb 24;292(8):3506-3516. doi: 10.1074/jbc.M116.768077. Epub 2017 Jan 18.


Patterning of papillae on the mouse tongue: A system for the quantitative assessment of planar cell polarity signaling.

Wang Y, Williams J, Rattner A, Wu S, Bassuk AG, Goffinet AM, Nathans J.

Dev Biol. 2016 Nov 15;419(2):298-310. doi: 10.1016/j.ydbio.2016.09.004. Epub 2016 Sep 6.


How scientists can reduce their carbon footprint.

Nathans J, Sterling P.

Elife. 2016 Mar 31;5. pii: e15928. doi: 10.7554/eLife.15928.


Frizzled Receptors in Development and Disease.

Wang Y, Chang H, Rattner A, Nathans J.

Curr Top Dev Biol. 2016;117:113-39. doi: 10.1016/bs.ctdb.2015.11.028. Epub 2016 Jan 27. Review.


Epigenomic landscapes of retinal rods and cones.

Mo A, Luo C, Davis FP, Mukamel EA, Henry GL, Nery JR, Urich MA, Picard S, Lister R, Eddy SR, Beer MA, Ecker JR, Nathans J.

Elife. 2016 Mar 7;5:e11613. doi: 10.7554/eLife.11613.


Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.

Zhou Y, Williams J, Smallwood PM, Nathans J.

PLoS One. 2015 Dec 2;10(12):e0143650. doi: 10.1371/journal.pone.0143650. eCollection 2015.


The spatio-temporal domains of Frizzled6 action in planar polarity control of hair follicle orientation.

Chang H, Smallwood PM, Williams J, Nathans J.

Dev Biol. 2016 Jan 1;409(1):181-193. doi: 10.1016/j.ydbio.2015.10.027. Epub 2015 Nov 10.


Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles.

Chang H, Cahill H, Smallwood PM, Wang Y, Nathans J.

PLoS Genet. 2015 Sep 29;11(9):e1005532. doi: 10.1371/journal.pgen.1005532. eCollection 2015.


Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems.

Hua ZL, Emiliani FE, Nathans J.

Neural Dev. 2015 Sep 23;10:21. doi: 10.1186/s13064-015-0049-3.


Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain.

Mo A, Mukamel EA, Davis FP, Luo C, Henry GL, Picard S, Urich MA, Nery JR, Sejnowski TJ, Lister R, Eddy SR, Ecker JR, Nathans J.

Neuron. 2015 Jun 17;86(6):1369-84. doi: 10.1016/j.neuron.2015.05.018.


Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis.

Vanhollebeke B, Stone OA, Bostaille N, Cho C, Zhou Y, Maquet E, Gauquier A, Cabochette P, Fukuhara S, Mochizuki N, Nathans J, Stainier DY.

Elife. 2015 Jun 8;4. doi: 10.7554/eLife.06489.

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