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Items: 1 to 20 of 29

1.

Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human.

Barel LA, Mulard LA.

Hum Vaccin Immunother. 2019;15(6):1338-1356. doi: 10.1080/21645515.2019.1606972.

2.

ADP-heptose is a newly identified pathogen-associated molecular pattern of Shigella flexneri.

García-Weber D, Dangeard AS, Cornil J, Thai L, Rytter H, Zamyatina A, Mulard LA, Arrieumerlou C.

EMBO Rep. 2018 Dec;19(12). pii: e46943. doi: 10.15252/embr.201846943. Epub 2018 Nov 19.

PMID:
30455202
3.

Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens.

Kunstmann S, Scheidt T, Buchwald S, Helm A, Mulard LA, Fruth A, Barbirz S.

Viruses. 2018 Aug 15;10(8). pii: E431. doi: 10.3390/v10080431.

4.

Dirhamnolipids secreted from Pseudomonas aeruginosa modify anjpegungal susceptibility of Aspergillus fumigatus by inhibiting β1,3 glucan synthase activity.

Briard B, Rasoldier V, Bomme P, ElAouad N, Guerreiro C, Chassagne P, Muszkieta L, Latgé JP, Mulard L, Beauvais A.

ISME J. 2017 Jul;11(7):1578-1591. doi: 10.1038/ismej.2017.32. Epub 2017 Mar 24.

5.

Efficient Iterative Synthesis of O-Acetylated Tri- to Pentadecasaccharides Related to the Lipopolysaccharide of Shigella flexneri Type 3 a through Di- and Trisaccharide Glycosyl Donors.

Hu Z, Bongat White AF, Mulard LA.

Chem Asian J. 2017 Feb 16;12(4):419-439. doi: 10.1002/asia.201600819. Epub 2017 Jan 12.

PMID:
27385615
6.

Detailed Investigation of the Immunodominant Role of O-Antigen Stoichiometric O-Acetylation as Revealed by Chemical Synthesis, Immunochemistry, Solution Conformation and STD-NMR Spectroscopy for Shigella flexneri 3a.

Boutet J, Blasco P, Guerreiro C, Thouron F, Dartevelle S, Nato F, Cañada FJ, Ardá A, Phalipon A, Jiménez-Barbero J, Mulard LA.

Chemistry. 2016 Jul 25;22(31):10892-911. doi: 10.1002/chem.201600567. Epub 2016 Jul 4.

PMID:
27376496
7.

A Synthetic Carbohydrate Conjugate Vaccine Candidate against Shigellosis: Improved Bioconjugation and Impact of Alum on Immunogenicity.

van der Put RM, Kim TH, Guerreiro C, Thouron F, Hoogerhout P, Sansonetti PJ, Westdijk J, Stork M, Phalipon A, Mulard LA.

Bioconjug Chem. 2016 Apr 20;27(4):883-92. doi: 10.1021/acs.bioconjchem.5b00617. Epub 2016 Mar 21.

PMID:
26918643
8.

Investigation on the Synthesis of Shigella flexneri Specific Oligosaccharides Using Disaccharides as Potential Transglucosylase Acceptor Substrates.

Salamone S, Guerreiro C, Cambon E, Hargreaves JM, Tarrat N, Remaud-Siméon M, André I, Mulard LA.

J Org Chem. 2015 Nov 20;80(22):11237-57. doi: 10.1021/acs.joc.5b01407. Epub 2015 Nov 10.

PMID:
26340432
9.

Programmed chemo-enzymatic synthesis of the oligosaccharide component of a carbohydrate-based antibacterial vaccine candidate.

Salamone S, Guerreiro C, Cambon E, André I, Remaud-Siméon M, Mulard LA.

Chem Commun (Camb). 2015 Feb 14;51(13):2581-4. doi: 10.1039/c4cc08805k.

PMID:
25569152
10.

Development and evaluation of a dipstick diagnostic test for Neisseria meningitidis serogroup X.

Agnememel A, Traincard F, Dartevelle S, Mulard L, Mahamane AE, Oukem-Boyer OO, Denizon M, Kacou-N Douba A, Dosso M, Gake B, Lombart JP, Taha MK.

J Clin Microbiol. 2015 Feb;53(2):449-54. doi: 10.1128/JCM.02444-14. Epub 2014 Nov 19.

11.

Synthesis of the zwitterionic repeating unit of the O-antigen from Shigella sonnei and chain elongation at both ends.

Pfister HB, Mulard LA.

Org Lett. 2014 Sep 19;16(18):4892-5. doi: 10.1021/ol502395k. Epub 2014 Sep 11.

PMID:
25210812
12.

Linear synthesis of the branched pentasaccharide repeats of O-antigens from Shigella flexneri 1a and 1b demonstrating the major steric hindrance associated with type-specific glucosylation.

Hargreaves JM, Le Guen Y, Guerreiro C, Descroix K, Mulard LA.

Org Biomol Chem. 2014 Oct 21;12(39):7728-49. doi: 10.1039/c4ob01200c. Epub 2014 Aug 21.

PMID:
25141906
13.

Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity.

Gauthier C, Chassagne P, Theillet FX, Guerreiro C, Thouron F, Nato F, Delepierre M, Sansonetti PJ, Phalipon A, Mulard LA.

Org Biomol Chem. 2014 Jun 28;12(24):4218-32. doi: 10.1039/c3ob42586j.

PMID:
24836582
14.

Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain.

Coïc YM, Baleux F, Poyraz Ö, Thibeaux R, Labruyere E, Chretien F, Sobhani I, Lazure T, Wyplosz B, Schneider G, Mulard L, Sansonetti PJ, Marteyn BS.

J Biol Chem. 2012 May 4;287(19):15916-22. doi: 10.1074/jbc.M111.310003. Epub 2012 Mar 16.

15.

Dynamic aspects of antibody:oligosaccharide complexes characterized by molecular dynamics simulations and saturation transfer difference nuclear magnetic resonance.

Theillet FX, Frank M, Vulliez-Le Normand B, Simenel C, Hoos S, Chaffotte A, Bélot F, Guerreiro C, Nato F, Phalipon A, Mulard LA, Delepierre M.

Glycobiology. 2011 Dec;21(12):1570-9. doi: 10.1093/glycob/cwr059. Epub 2011 May 24.

PMID:
21610193
16.

Effects of backbone substitutions on the conformational behavior of Shigella flexneri O-antigens: implications for vaccine strategy.

Theillet FX, Simenel C, Guerreiro C, Phalipon A, Mulard LA, Delepierre M.

Glycobiology. 2011 Jan;21(1):109-21. doi: 10.1093/glycob/cwq136. Epub 2010 Oct 28.

PMID:
21030536
17.

Structural mimicry of O-antigen by a peptide revealed in a complex with an antibody raised against Shigella flexneri serotype 2a.

Theillet FX, Saul FA, Vulliez-Le Normand B, Hoos S, Felici F, Weintraub A, Mulard LA, Phalipon A, Delepierre M, Bentley GA.

J Mol Biol. 2009 May 15;388(4):839-50. doi: 10.1016/j.jmb.2009.03.057. Epub 2009 Mar 27.

PMID:
19328810
19.

A synthetic carbohydrate-protein conjugate vaccine candidate against Shigella flexneri 2a infection.

Phalipon A, Tanguy M, Grandjean C, Guerreiro C, Bélot F, Cohen D, Sansonetti PJ, Mulard LA.

J Immunol. 2009 Feb 15;182(4):2241-7. doi: 10.4049/jimmunol.0803141.

20.

Vaccination against shigellosis: is it the path that is difficult or is it the difficult that is the path?

Phalipon A, Mulard LA, Sansonetti PJ.

Microbes Infect. 2008 Jul;10(9):1057-62. doi: 10.1016/j.micinf.2008.07.016. Epub 2008 Jul 10. Review.

PMID:
18672087

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