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Items: 17


Increased Inflammation in Pericardial Fluid Persists 48 Hours After Cardiac Surgery.

Butts B, Goeddel LA, George DJ, Steele C, Davies JE, Wei CC, Varagic J, George JF, Ferrario CM, Melby SJ, Dell'Italia LJ.

Circulation. 2017 Dec 5;136(23):2284-2286. doi: 10.1161/CIRCULATIONAHA.117.029589. No abstract available.


Desmin loss and mitochondrial damage precede left ventricular systolic failure in volume overload heart failure.

Guichard JL, Rogowski M, Agnetti G, Fu L, Powell P, Wei CC, Collawn J, Dell'Italia LJ.

Am J Physiol Heart Circ Physiol. 2017 Jul 1;313(1):H32-H45. doi: 10.1152/ajpheart.00027.2017. Epub 2017 Apr 28.


Increased fibroblast chymase production mediates procollagen autophagic digestion in volume overload.

Fu L, Wei CC, Powell PC, Bradley WE, Ahmad S, Ferrario CM, Collawn JF, Dell'Italia LJ.

J Mol Cell Cardiol. 2016 Mar;92:1-9. doi: 10.1016/j.yjmcc.2016.01.019. Epub 2016 Jan 22.


Volume overload induces autophagic degradation of procollagen in cardiac fibroblasts.

Fu L, Wei CC, Powell PC, Bradley WE, Collawn JF, Dell'Italia LJ.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):241-250. doi: 10.1016/j.yjmcc.2015.10.027. Epub 2015 Oct 24.


Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog.

Zheng J, Wei CC, Hase N, Shi K, Killingsworth CR, Litovsky SH, Powell PC, Kobayashi T, Ferrario CM, Rab A, Aban I, Collawn JF, Dell'Italia LJ.

PLoS One. 2014 Apr 14;9(4):e94732. doi: 10.1371/journal.pone.0094732. eCollection 2014.


Whole-genome profiling highlights the molecular complexity underlying eccentric cardiac hypertrophy.

Barnes J, Pat B, Chen YW, Powell PC, Bradley WE, Zheng J, Karki A, Cui X, Guichard J, Wei CC, Collawn J, Dell'Italia LJ.

Ther Adv Cardiovasc Dis. 2014 Mar 31;8(3):97-118. [Epub ahead of print]


Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload.

Fetterman JL, Zelickson BR, Johnson LW, Moellering DR, Westbrook DG, Pompilius M, Sammy MJ, Johnson M, Dunham-Snary KJ, Cao X, Bradley WE, Zhang J, Wei CC, Chacko B, Schurr TG, Kesterson RA, Dell'italia LJ, Darley-Usmar VM, Welch DR, Ballinger SW.

Biochem J. 2013 Oct 15;455(2):157-67. doi: 10.1042/BJ20130029. Erratum in: Biochem J. 2013 Oct 1;455(1):147.


Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss.

Wei CC, Chen Y, Powell LC, Zheng J, Shi K, Bradley WE, Powell PC, Ahmad S, Ferrario CM, Dell'Italia LJ.

PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.


Novel insights into interactions between mitochondria and xanthine oxidase in acute cardiac volume overload.

Gladden JD, Zelickson BR, Wei CC, Ulasova E, Zheng J, Ahmed MI, Chen Y, Bamman M, Ballinger S, Darley-Usmar V, Dell'Italia LJ.

Free Radic Biol Med. 2011 Dec 1;51(11):1975-84. doi: 10.1016/j.freeradbiomed.2011.08.022. Epub 2011 Aug 30.


Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation.

Pat B, Chen Y, Killingsworth C, Gladden JD, Shi K, Zheng J, Powell PC, Walcott G, Ahmed MI, Gupta H, Desai R, Wei CC, Hase N, Kobayashi T, Sabri A, Granzier H, Denney T, Tillson M, Dillon AR, Husain A, Dell'italia LJ.

Circulation. 2010 Oct 12;122(15):1488-95. doi: 10.1161/CIRCULATIONAHA.109.921619. Epub 2010 Sep 27.


Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents.

Wei CC, Hase N, Inoue Y, Bradley EW, Yahiro E, Li M, Naqvi N, Powell PC, Shi K, Takahashi Y, Saku K, Urata H, Dell'italia LJ, Husain A.

J Clin Invest. 2010 Apr;120(4):1229-39. doi: 10.1172/JCI39345. Epub 2010 Mar 24.


A thrombospondin-1 antagonist of transforming growth factor-beta activation blocks cardiomyopathy in rats with diabetes and elevated angiotensin II.

Belmadani S, Bernal J, Wei CC, Pallero MA, Dell'italia L, Murphy-Ullrich JE, Berecek KH.

Am J Pathol. 2007 Sep;171(3):777-89. Epub 2007 Jul 19.


Short-acting beta-adrenergic antagonist esmolol given at reperfusion improves survival after prolonged ventricular fibrillation.

Killingsworth CR, Wei CC, Dell'Italia LJ, Ardell JL, Kingsley MA, Smith WM, Ideker RE, Walcott GP.

Circulation. 2004 May 25;109(20):2469-74. Epub 2004 May 3.


Beta1-adrenergic receptor blockade attenuates angiotensin II-mediated catecholamine release into the cardiac interstitium in mitral regurgitation.

Tallaj J, Wei CC, Hankes GH, Holland M, Rynders P, Dillon AR, Ardell JL, Armour JA, Lucchesi PA, Dell'Italia LJ.

Circulation. 2003 Jul 15;108(2):225-30. Epub 2003 Jul 7.


Differential ANG II generation in plasma and tissue of mice with decreased expression of the ACE gene.

Wei CC, Tian B, Perry G, Meng QC, Chen YF, Oparil S, Dell'Italia LJ.

Am J Physiol Heart Circ Physiol. 2002 Jun;282(6):H2254-8.


Angiotensin II receptor blockade does not improve left ventricular function and remodeling in subacute mitral regurgitation in the dog.

Perry GJ, Wei CC, Hankes GH, Dillon SR, Rynders P, Mukherjee R, Spinale FG, Dell'Italia LJ.

J Am Coll Cardiol. 2002 Apr 17;39(8):1374-9.


Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivo.

Wei CC, Ferrario CM, Brosnihan KB, Farrell DM, Bradley WE, Jaffa AA, Dell'Italia LJ.

J Pharmacol Exp Ther. 2002 Jan;300(1):324-9.

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