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Items: 18


Targeting the Sigma-1 Receptor via Pridopidine Ameliorates Central Features of ALS Pathology in a SOD1G93A Model.

Ionescu A, Gradus T, Altman T, Maimon R, Saraf Avraham N, Geva M, Hayden M, Perlson E.

Cell Death Dis. 2019 Mar 1;10(3):210. doi: 10.1038/s41419-019-1451-2.


Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS.

Gershoni-Emek N, Altman T, Ionescu A, Costa CJ, Gradus-Pery T, Willis DE, Perlson E.

Front Mol Neurosci. 2018 Sep 5;11:311. doi: 10.3389/fnmol.2018.00311. eCollection 2018.


Generation and comparative genomics of synthetic dengue viruses.

Goz E, Tsalenchuck Y, Benaroya RO, Zafrir Z, Atar S, Altman T, Julander J, Tuller T.

BMC Bioinformatics. 2018 May 8;19(Suppl 6):140. doi: 10.1186/s12859-018-2132-3.


The receptor tyrosine kinase TrkB signals without dimerization at the plasma membrane.

Zahavi EE, Steinberg N, Altman T, Chein M, Joshi Y, Gradus-Pery T, Perlson E.

Sci Signal. 2018 May 8;11(529). pii: eaao4006. doi: 10.1126/scisignal.aao4006.


A geographically-diverse collection of 418 human gut microbiome pathway genome databases.

Hahn AS, Altman T, Konwar KM, Hanson NW, Kim D, Relman DA, Dill DL, Hallam SJ.

Sci Data. 2017 Apr 11;4:170035. doi: 10.1038/sdata.2017.35.


ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models.

Rotem N, Magen I, Ionescu A, Gershoni-Emek N, Altman T, Costa CJ, Gradus T, Pasmanik-Chor M, Willis DE, Ben-Dov IZ, Hornstein E, Perlson E.

Sci Rep. 2017 Mar 16;7:44500. doi: 10.1038/srep44500.


Metabolic pathways for the whole community.

Hanson NW, Konwar KM, Hawley AK, Altman T, Karp PD, Hallam SJ.

BMC Genomics. 2014 Jul 22;15:619. doi: 10.1186/1471-2164-15-619.


Finding sequences for over 270 orphan enzymes.

Shearer AG, Altman T, Rhee CD.

PLoS One. 2014 May 14;9(5):e97250. doi: 10.1371/journal.pone.0097250. eCollection 2014.


PortEco: a resource for exploring bacterial biology through high-throughput data and analysis tools.

Hu JC, Sherlock G, Siegele DA, Aleksander SA, Ball CA, Demeter J, Gouni S, Holland TA, Karp PD, Lewis JE, Liles NM, McIntosh BK, Mi H, Muruganujan A, Wymore F, Thomas PD, Altman T.

Nucleic Acids Res. 2014 Jan;42(Database issue):D677-84. doi: 10.1093/nar/gkt1203. Epub 2013 Nov 26. Erratum in: Nucleic Acids Res. 2014 Oct 29;42(19):12330.


The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases.

Caspi R, Altman T, Billington R, Dreher K, Foerster H, Fulcher CA, Holland TA, Keseler IM, Kothari A, Kubo A, Krummenacker M, Latendresse M, Mueller LA, Ong Q, Paley S, Subhraveti P, Weaver DS, Weerasinghe D, Zhang P, Karp PD.

Nucleic Acids Res. 2014 Jan;42(Database issue):D459-71. doi: 10.1093/nar/gkt1103. Epub 2013 Nov 12.


Use of electronic cigarettes among state tobacco cessation quitline callers.

Vickerman KA, Carpenter KM, Altman T, Nash CM, Zbikowski SM.

Nicotine Tob Res. 2013 Oct;15(10):1787-91. doi: 10.1093/ntr/ntt061. Epub 2013 May 8.


A systematic comparison of the MetaCyc and KEGG pathway databases.

Altman T, Travers M, Kothari A, Caspi R, Karp PD.

BMC Bioinformatics. 2013 Mar 27;14:112. doi: 10.1186/1471-2105-14-112.


Data mining in the MetaCyc family of pathway databases.

Karp PD, Paley S, Altman T.

Methods Mol Biol. 2013;939:183-200. doi: 10.1007/978-1-62703-107-3_12.


The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases.

Caspi R, Altman T, Dreher K, Fulcher CA, Subhraveti P, Keseler IM, Kothari A, Krummenacker M, Latendresse M, Mueller LA, Ong Q, Paley S, Pujar A, Shearer AG, Travers M, Weerasinghe D, Zhang P, Karp PD.

Nucleic Acids Res. 2012 Jan;40(Database issue):D742-53. doi: 10.1093/nar/gkr1014. Epub 2011 Nov 18.


EcoCyc: a comprehensive database of Escherichia coli biology.

Keseler IM, Collado-Vides J, Santos-Zavaleta A, Peralta-Gil M, Gama-Castro S, Muñiz-Rascado L, Bonavides-Martinez C, Paley S, Krummenacker M, Altman T, Kaipa P, Spaulding A, Pacheco J, Latendresse M, Fulcher C, Sarker M, Shearer AG, Mackie A, Paulsen I, Gunsalus RP, Karp PD.

Nucleic Acids Res. 2011 Jan;39(Database issue):D583-90. doi: 10.1093/nar/gkq1143. Epub 2010 Nov 21.


HIGEDA: a hierarchical gene-set genetics based algorithm for finding subtle motifs in biological sequences.

Le T, Altman T, Gardiner K.

Bioinformatics. 2010 Feb 1;26(3):302-9. doi: 10.1093/bioinformatics/btp676. Epub 2009 Dec 8.


Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology.

Karp PD, Paley SM, Krummenacker M, Latendresse M, Dale JM, Lee TJ, Kaipa P, Gilham F, Spaulding A, Popescu L, Altman T, Paulsen I, Keseler IM, Caspi R.

Brief Bioinform. 2010 Jan;11(1):40-79. doi: 10.1093/bib/bbp043. Epub 2009 Dec 2.


The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases.

Caspi R, Altman T, Dale JM, Dreher K, Fulcher CA, Gilham F, Kaipa P, Karthikeyan AS, Kothari A, Krummenacker M, Latendresse M, Mueller LA, Paley S, Popescu L, Pujar A, Shearer AG, Zhang P, Karp PD.

Nucleic Acids Res. 2010 Jan;38(Database issue):D473-9. doi: 10.1093/nar/gkp875. Epub 2009 Oct 22.

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