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Items: 14

1.

Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.

Ordureau A, Paulo JA, Zhang W, Ahfeldt T, Zhang J, Cohn EF, Hou Z, Heo JM, Rubin LL, Sidhu SS, Gygi SP, Harper JW.

Mol Cell. 2018 Apr 19;70(2):211-227.e8. doi: 10.1016/j.molcel.2018.03.012. Epub 2018 Apr 12.

PMID:
29656925
2.

Studying human disease using human neurons.

Ahfeldt T, Litterman NK, Rubin LL.

Brain Res. 2017 Feb 1;1656:40-48. doi: 10.1016/j.brainres.2016.03.051. Epub 2016 Apr 6. Review.

3.

Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities.

Madison JM, Zhou F, Nigam A, Hussain A, Barker DD, Nehme R, van der Ven K, Hsu J, Wolf P, Fleishman M, O'Dushlaine C, Rose S, Chambert K, Lau FH, Ahfeldt T, Rueckert EH, Sheridan SD, Fass DM, Nemesh J, Mullen TE, Daheron L, McCarroll S, Sklar P, Perlis RH, Haggarty SJ.

Mol Psychiatry. 2015 Jun;20(6):703-17. doi: 10.1038/mp.2015.7. Epub 2015 Mar 3.

4.

A TALEN genome-editing system for generating human stem cell-based disease models.

Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA.

Cell Stem Cell. 2013 Feb 7;12(2):238-51. doi: 10.1016/j.stem.2012.11.011. Epub 2012 Dec 13.

5.

Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs.

Mou H, Zhao R, Sherwood R, Ahfeldt T, Lapey A, Wain J, Sicilian L, Izvolsky K, Musunuru K, Cowan C, Rajagopal J.

Cell Stem Cell. 2012 Apr 6;10(4):385-97. doi: 10.1016/j.stem.2012.01.018. Erratum in: Cell Stem Cell. 2012 May 4;10(5):635.

6.

Programming human pluripotent stem cells into white and brown adipocytes.

Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA.

Nat Cell Biol. 2012 Jan 15;14(2):209-19. doi: 10.1038/ncb2411.

7.

Efficient culturing and genetic manipulation of human pluripotent stem cells.

Schinzel RT, Ahfeldt T, Lau FH, Lee YK, Cowley A, Shen T, Peters D, Lum DH, Cowan CA.

PLoS One. 2011;6(12):e27495. doi: 10.1371/journal.pone.0027495. Epub 2011 Dec 15.

8.

Pattern specification and immune response transcriptional signatures of pericardial and subcutaneous adipose tissue.

Lau FH, Deo RC, Mowrer G, Caplin J, Ahfeldt T, Kaplan A, Ptaszek L, Walker JD, Rosengard BR, Cowan CA.

PLoS One. 2011;6(10):e26092. doi: 10.1371/journal.pone.0026092. Epub 2011 Oct 11.

9.

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ.

Cell Stem Cell. 2010 Nov 5;7(5):618-30. doi: 10.1016/j.stem.2010.08.012. Epub 2010 Sep 30.

10.

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.

Musunuru K, Strong A, Frank-Kamenetsky M, Lee NE, Ahfeldt T, Sachs KV, Li X, Li H, Kuperwasser N, Ruda VM, Pirruccello JP, Muchmore B, Prokunina-Olsson L, Hall JL, Schadt EE, Morales CR, Lund-Katz S, Phillips MC, Wong J, Cantley W, Racie T, Ejebe KG, Orho-Melander M, Melander O, Koteliansky V, Fitzgerald K, Krauss RM, Cowan CA, Kathiresan S, Rader DJ.

Nature. 2010 Aug 5;466(7307):714-9. doi: 10.1038/nature09266.

11.

Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells.

Eminli S, Foudi A, Stadtfeld M, Maherali N, Ahfeldt T, Mostoslavsky G, Hock H, Hochedlinger K.

Nat Genet. 2009 Sep;41(9):968-76. doi: 10.1038/ng.428. Epub 2009 Aug 9.

12.

Induced pluripotent stem (iPS) cells: an up-to-the-minute review.

Lau F, Ahfeldt T, Osafune K, Akustsu H, Cowan CA.

F1000 Biol Rep. 2009 Nov 16;1:84. doi: 10.3410/B1-84.

13.

A high-efficiency system for the generation and study of human induced pluripotent stem cells.

Maherali N, Ahfeldt T, Rigamonti A, Utikal J, Cowan C, Hochedlinger K.

Cell Stem Cell. 2008 Sep 11;3(3):340-5. doi: 10.1016/j.stem.2008.08.003.

14.

Disease-specific induced pluripotent stem cells.

Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, Lensch MW, Cowan C, Hochedlinger K, Daley GQ.

Cell. 2008 Sep 5;134(5):877-86. doi: 10.1016/j.cell.2008.07.041. Epub 2008 Aug 7.

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