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Items: 1 to 20 of 44

1.

Live-attenuated Mycobacterium tuberculosis vaccine MTBVAC versus BCG in adults and neonates: a randomised controlled, double-blind dose-escalation trial.

Tameris M, Mearns H, Penn-Nicholson A, Gregg Y, Bilek N, Mabwe S, Geldenhuys H, Shenje J, Luabeya AKK, Murillo I, Doce J, Aguilo N, Marinova D, Puentes E, Rodríguez E, Gonzalo-Asensio J, Fritzell B, Thole J, Martin C, Scriba TJ, Hatherill M; MTBVAC Clinical Trial Team.

Lancet Respir Med. 2019 Aug 12. pii: S2213-2600(19)30251-6. doi: 10.1016/S2213-2600(19)30251-6. [Epub ahead of print]

PMID:
31416768
2.

TIPICO IX: report of the 9th interactive infectious disease workshop on infectious diseases and vaccines.

Martinón-Torres F, Bosch X, Rappuoli R, Ladhani S, Redondo E, Vesikari T, García-Sastre A, Rivero-Calle I, Gómez-Rial J, Salas A, Martín C, Finn A, Butler R.

Hum Vaccin Immunother. 2019 Jun 3:1-11. doi: 10.1080/21645515.2019.1609823. [Epub ahead of print]

PMID:
31158041
3.

Comparative Metabolomics between Mycobacterium tuberculosis and the MTBVAC Vaccine Candidate.

Díaz C, Pérez Del Palacio J, Valero-Guillén PL, Mena García P, Pérez I, Vicente F, Martín C, Genilloud O, Sánchez Pozo A, Gonzalo-Asensio J.

ACS Infect Dis. 2019 Aug 9;5(8):1317-1326. doi: 10.1021/acsinfecdis.9b00008. Epub 2019 May 30.

PMID:
31099236
4.

MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against Mycobacterium tuberculosis in Mice.

Broset E, Saubi N, Guitart N, Aguilo N, Uranga S, Kilpeläinen A, Eto Y, Hanke T, Gonzalo-Asensio J, Martín C, Joseph-Munné J.

Mol Ther Methods Clin Dev. 2019 Feb 7;13:253-264. doi: 10.1016/j.omtm.2019.01.014. eCollection 2019 Jun 14.

5.

Therapeutic efficacy of the live-attenuated Mycobacterium tuberculosis vaccine, MTBVAC, in a preclinical model of bladder cancer.

Alvarez-Arguedas S, Uranga S, Martín M, Elizalde J, Gomez AB, Julián E, Nardelli-Haefliger D, Martín C, Aguilo N.

Transl Res. 2018 Jul;197:32-42. doi: 10.1016/j.trsl.2018.03.004. Epub 2018 Apr 6.

PMID:
29702078
6.

Vaccination against tuberculosis.

Martin C, Aguilo N, Gonzalo-Asensio J.

Enferm Infecc Microbiol Clin. 2018 Dec;36(10):648-656. doi: 10.1016/j.eimc.2018.02.006. Epub 2018 Apr 5. English, Spanish.

PMID:
29627126
7.

MTBVAC: Attenuating the Human Pathogen of Tuberculosis (TB) Toward a Promising Vaccine against the TB Epidemic.

Gonzalo-Asensio J, Marinova D, Martin C, Aguilo N.

Front Immunol. 2017 Dec 15;8:1803. doi: 10.3389/fimmu.2017.01803. eCollection 2017. Review.

8.

Breaking Transmission with Vaccines: The Case of Tuberculosis.

Gonzalo-Asensio J, Aguilo N, Marinova D, Martin C.

Microbiol Spectr. 2017 Jul;5(4). doi: 10.1128/microbiolspec.MTBP-0001-2016. Review.

PMID:
28710848
9.

Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis.

Aguilo N, Gonzalo-Asensio J, Alvarez-Arguedas S, Marinova D, Gomez AB, Uranga S, Spallek R, Singh M, Audran R, Spertini F, Martin C.

Nat Commun. 2017 Jul 14;8:16085. doi: 10.1038/ncomms16085.

10.

Evaluation of the Mycobacterium tuberculosis SO2 vaccine using a natural tuberculosis infection model in goats.

Bezos J, Casal C, Álvarez J, Roy A, Romero B, Rodríguez-Bertos A, Bárcena C, Díez A, Juste R, Gortázar C, Puentes E, Aguiló N, Martín C, de Juan L, Domínguez L.

Vet J. 2017 May;223:60-67. doi: 10.1016/j.tvjl.2017.04.006. Epub 2017 May 3.

PMID:
28671074
11.

MTBVAC from discovery to clinical trials in tuberculosis-endemic countries.

Marinova D, Gonzalo-Asensio J, Aguilo N, Martin C.

Expert Rev Vaccines. 2017 Jun;16(6):565-576. doi: 10.1080/14760584.2017.1324303. Epub 2017 May 12. Review.

PMID:
28447476
12.

Revaccination of Guinea Pigs With the Live Attenuated Mycobacterium tuberculosis Vaccine MTBVAC Improves BCG's Protection Against Tuberculosis.

Clark S, Lanni F, Marinova D, Rayner E, Martin C, Williams A.

J Infect Dis. 2017 Sep 1;216(5):525-533. doi: 10.1093/infdis/jix030.

PMID:
28329234
13.

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice.

Uranga S, Marinova D, Martin C, Aguilo N.

J Vis Exp. 2016 Sep 19;(115). doi: 10.3791/54440.

14.

Vaccination Against Tuberculosis With Whole-Cell Mycobacterial Vaccines.

Scriba TJ, Kaufmann SH, Henri Lambert P, Sanicas M, Martin C, Neyrolles O.

J Infect Dis. 2016 Sep 1;214(5):659-64. doi: 10.1093/infdis/jiw228. Epub 2016 May 30. Review.

PMID:
27247343
15.

Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo.

Uranga S, Marinova D, Martin C, Pardo J, Aguilo N.

PLoS One. 2016 Apr 7;11(4):e0153028. doi: 10.1371/journal.pone.0153028. eCollection 2016.

16.

MTBVAC vaccine is safe, immunogenic and confers protective efficacy against Mycobacterium tuberculosis in newborn mice.

Aguilo N, Uranga S, Marinova D, Monzon M, Badiola J, Martin C.

Tuberculosis (Edinb). 2016 Jan;96:71-4. doi: 10.1016/j.tube.2015.10.010. Epub 2015 Nov 30.

17.

Evaluation of the immunogenicity and diagnostic interference caused by M. tuberculosis SO2 vaccination against tuberculosis in goats.

Bezos J, Casal C, Puentes E, Díez-Guerrier A, Romero B, Aguiló N, de Juan L, Martín C, Domínguez L.

Res Vet Sci. 2015 Dec;103:73-9. doi: 10.1016/j.rvsc.2015.09.017. Epub 2015 Sep 25.

PMID:
26679799
18.

Safety of human immunisation with a live-attenuated Mycobacterium tuberculosis vaccine: a randomised, double-blind, controlled phase I trial.

Spertini F, Audran R, Chakour R, Karoui O, Steiner-Monard V, Thierry AC, Mayor CE, Rettby N, Jaton K, Vallotton L, Lazor-Blanchet C, Doce J, Puentes E, Marinova D, Aguilo N, Martin C.

Lancet Respir Med. 2015 Dec;3(12):953-62. doi: 10.1016/S2213-2600(15)00435-X. Epub 2015 Nov 17.

PMID:
26598141
19.

Pulmonary but Not Subcutaneous Delivery of BCG Vaccine Confers Protection to Tuberculosis-Susceptible Mice by an Interleukin 17-Dependent Mechanism.

Aguilo N, Alvarez-Arguedas S, Uranga S, Marinova D, Monzón M, Badiola J, Martin C.

J Infect Dis. 2016 Mar 1;213(5):831-9. doi: 10.1093/infdis/jiv503. Epub 2015 Oct 22.

PMID:
26494773
20.

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