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The gastric microbiome, its interaction with Helicobacter pylori, and its potential role in the progression to stomach cancer.

Noto JM, Peek RM Jr.

PLoS Pathog. 2017 Oct 5;13(10):e1006573. doi: 10.1371/journal.ppat.1006573. eCollection 2017 Oct. Review. No abstract available.


MicroRNA-148a-3p enhances cisplatin cytotoxicity in gastric cancer through mitochondrial fission induction and cyto-protective autophagy suppression.

Li B, Wang W, Li Z, Chen Z, Zhi X, Xu J, Li Q, Wang L, Huang X, Wang L, Wei S, Sun G, Zhang X, He Z, Zhang L, Zhang D, Xu H, El-Rifai W, Xu Z.

Cancer Lett. 2017 Dec 1;410:212-227. doi: 10.1016/j.canlet.2017.09.035. Epub 2017 Sep 28.


Linked read sequencing resolves complex genomic rearrangements in gastric cancer metastases.

Greer SU, Nadauld LD, Lau BT, Chen J, Wood-Bouwens C, Ford JM, Kuo CJ, Ji HP.

Genome Med. 2017 Jun 19;9(1):57. doi: 10.1186/s13073-017-0447-8.


Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.

Cho SY, Park JW, Liu Y, Park YS, Kim JH, Yang H, Um H, Ko WR, Lee BI, Kwon SY, Ryu SW, Kwon CH, Park DY, Lee JH, Lee SI, Song KS, Hur H, Han SU, Chang H, Kim SJ, Kim BS, Yook JH, Yoo MW, Kim BS, Lee IS, Kook MC, Thiessen N, He A, Stewart C, Dunford A, Kim J, Shih J, Saksena G, Cherniack AD, Schumacher S, Weiner AT, Rosenberg M, Getz G, Yang EG, Ryu MH, Bass AJ, Kim HK.

Gastroenterology. 2017 Aug;153(2):536-549.e26. doi: 10.1053/j.gastro.2017.05.012. Epub 2017 May 15.


Prolyl isomerase PIN1 regulates the stability, transcriptional activity and oncogenic potential of BRD4.

Hu X, Dong SH, Chen J, Zhou XZ, Chen R, Nair S, Lu KP, Chen LF.

Oncogene. 2017 Sep 7;36(36):5177-5188. doi: 10.1038/onc.2017.137. Epub 2017 May 8.


Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer.

Chen I, Mathews-Greiner L, Li D, Abisoye-Ogunniyan A, Ray S, Bian Y, Shukla V, Zhang X, Guha R, Thomas C, Gryder B, Zacharia A, Beane JD, Ravichandran S, Ferrer M, Rudloff U.

J Transl Med. 2017 May 1;15(1):92. doi: 10.1186/s12967-017-1197-5.


GLI1-mediated regulation of side population is responsible for drug resistance in gastric cancer.

Yu B, Gu D, Zhang X, Li J, Liu B, Xie J.

Oncotarget. 2017 Apr 18;8(16):27412-27427. doi: 10.18632/oncotarget.16174.


Dissecting the regulation of EBV's BART miRNAs in carcinomas.

Yang YC, Liem A, Lambert PF, Sugden B.

Virology. 2017 May;505:148-154. doi: 10.1016/j.virol.2017.02.013. Epub 2017 Mar 1.


Rapid evolution of distinct Helicobacter pylori subpopulations in the Americas.

Thorell K, Yahara K, Berthenet E, Lawson DJ, Mikhail J, Kato I, Mendez A, Rizzato C, Bravo MM, Suzuki R, Yamaoka Y, Torres J, Sheppard SK, Falush D.

PLoS Genet. 2017 Feb 23;13(2):e1006546. doi: 10.1371/journal.pgen.1006546. eCollection 2017 Feb. Erratum in: PLoS Genet. 2017 Apr 14;13(4):e1006730.


Discoidin domain receptor 1 activity drives an aggressive phenotype in gastric carcinoma.

Hur H, Ham IH, Lee D, Jin H, Aguilera KY, Oh HJ, Han SU, Kwon JE, Kim YB, Ding K, Brekken RA.

BMC Cancer. 2017 Jan 31;17(1):87. doi: 10.1186/s12885-017-3051-9.


Composite protective lifestyle factors and risk of developing gastric adenocarcinoma: the Singapore Chinese Health Study.

Wang Z, Koh WP, Jin A, Wang R, Yuan JM.

Br J Cancer. 2017 Feb 28;116(5):679-687. doi: 10.1038/bjc.2017.7. Epub 2017 Jan 26.


Stomach Cancer Following Hodgkin Lymphoma, Testicular Cancer and Cervical Cancer: A Pooled Analysis of Three International Studies with a Focus on Radiation Effects.

Gilbert ES, Curtis RE, Hauptmann M, Kleinerman RA, Lynch CF, Stovall M, Smith SA, Weathers R, Andersson M, Dores GM, Fraumeni JF Jr, Fossa SD, Hall P, Hodgson DC, Holowaty EJ, Joensuu H, Johannesen TB, Langmark F, Kaijser M, Pukkala E, Rajaraman P, Storm HH, Vaalavirta L, van den Belt-Dusebout AW, Aleman BM, Travis LB, Morton LM, van Leeuwen FE.

Radiat Res. 2017 Feb;187(2):186-195. doi: 10.1667/RR14453.1. Epub 2017 Jan 24.


Surgical Management of Adolescents and Young Adults With Gastrointestinal Stromal Tumors: A US Population-Based Analysis.

Fero KE, Coe TM, Fanta PT, Tang CM, Murphy JD, Sicklick JK.

JAMA Surg. 2017 May 1;152(5):443-451. doi: 10.1001/jamasurg.2016.5047.


MET tyrosine kinase receptor expression and amplification as prognostic biomarkers of survival in gastroesophageal adenocarcinoma.

Catenacci DV, Ang A, Liao WL, Shen J, O'Day E, Loberg RD, Cecchi F, Hembrough T, Ruzzo A, Graziano F.

Cancer. 2017 May 15;123(6):1061-1070. doi: 10.1002/cncr.30437. Epub 2016 Dec 7.


Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice.

Perez EM, Foley J, Tison T, Silva R, Ogembo JG.

Oncotarget. 2017 Mar 21;8(12):19255-19273. doi: 10.18632/oncotarget.13770.


Identification of primary tumors in patients presenting with metastatic gastroenteropancreatic neuroendocrine tumors.

Keck KJ, Maxwell JE, Menda Y, Bellizzi A, Dillon J, O'Dorisio TM, Howe JR.

Surgery. 2017 Jan;161(1):272-279. doi: 10.1016/j.surg.2016.05.055. Epub 2016 Nov 15.


Increased RhoA Activity Predicts Worse Overall Survival in Patients Undergoing Surgical Resection for Lauren Diffuse-Type Gastric Adenocarcinoma.

Chang KK, Cho SJ, Yoon C, Lee JH, Park DJ, Yoon SS.

Ann Surg Oncol. 2016 Dec;23(13):4238-4246. Epub 2016 Jun 30.


Fruit and vegetable consumption, Helicobacter pylori antibodies, and gastric cancer risk: A pooled analysis of prospective studies in China, Japan, and Korea.

Wang T, Cai H, Sasazuki S, Tsugane S, Zheng W, Cho ER, Jee SH, Michel A, Pawlita M, Xiang YB, Gao YT, Shu XO, You WC, Epplein M.

Int J Cancer. 2017 Feb 1;140(3):591-599. doi: 10.1002/ijc.30477. Epub 2016 Oct 31.


Complications of Feeding Jejunostomy Tubes in Patients with Gastroesophageal Cancer.

Choi AH, O'Leary MP, Merchant SJ, Sun V, Chao J, Raz DJ, Kim JY, Kim J.

J Gastrointest Surg. 2017 Feb;21(2):259-265. doi: 10.1007/s11605-016-3297-6. Epub 2016 Oct 26.


Morphology and genetics of pyloric gland adenomas in familial adenomatous polyposis.

Hackeng WM, Montgomery EA, Giardiello FM, Singhi AD, Debeljak M, Eshleman JR, Vieth M, Offerhaus GJ, Wood LD, Brosens LA.

Histopathology. 2017 Mar;70(4):549-557. doi: 10.1111/his.13105. Epub 2016 Dec 13.

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