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Items: 1 to 20 of 85


Metformin attenuates the onset of non-alcoholic fatty liver disease and affects intestinal microbiota and barrier in small intestine.

Brandt A, Hernández-Arriaga A, Kehm R, Sánchez V, Jin CJ, Nier A, Baumann A, Camarinha-Silva A, Bergheim I.

Sci Rep. 2019 Apr 30;9(1):6668. doi: 10.1038/s41598-019-43228-0.


Metabolic Abnormalities in Normal Weight Children Are Associated with Increased Visceral Fat Accumulation, Elevated Plasma Endotoxin Levels and a Higher Monosaccharide Intake.

Nier A, Brandt A, Baumann A, Conzelmann IB, Özel Y, Bergheim I.

Nutrients. 2019 Mar 18;11(3). pii: E652. doi: 10.3390/nu11030652.


Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis.

Liao L, Schneider KM, Galvez EJC, Frissen M, Marschall HU, Su H, Hatting M, Wahlström A, Haybaeck J, Puchas P, Mohs A, Peng J, Bergheim I, Nier A, Hennings J, Reißing J, Zimmermann HW, Longerich T, Strowig T, Liedtke C, Cubero FJ, Trautwein C.

Gut. 2019 Mar 14. pii: gutjnl-2018-316670. doi: 10.1136/gutjnl-2018-316670. [Epub ahead of print]


Nutritional Intake and the Risk for Non-Alcoholic Fatty Liver Disease (NAFLD).

Schattenberg JM, Bergheim I.

Nutrients. 2019 Mar 11;11(3). pii: E588. doi: 10.3390/nu11030588.


Beneficial Effects of Vitamin D Treatment in an Obese Mouse Model of Non-Alcoholic Steatohepatitis.

Jahn D, Dorbath D, Kircher S, Nier A, Bergheim I, Lenaerts K, Hermanns HM, Geier A.

Nutrients. 2019 Jan 3;11(1). pii: E77. doi: 10.3390/nu11010077.


Consumption of decaffeinated coffee protects against the development of early non-alcoholic steatohepatitis: Role of intestinal barrier function.

Brandt A, Nier A, Jin CJ, Baumann A, Jung F, Ribas V, García-Ruiz C, Fernández-Checa JC, Bergheim I.

Redox Biol. 2019 Feb;21:101092. doi: 10.1016/j.redox.2018.101092. Epub 2018 Dec 23.


Short-Term Isocaloric Intake of a Fructose- but not Glucose-Rich Diet Affects Bacterial Endotoxin Concentrations and Markers of Metabolic Health in Normal Weight Healthy Subjects.

Nier A, Brandt A, Rajcic D, Bruns T, Bergheim I.

Mol Nutr Food Res. 2019 Mar;63(6):e1800868. doi: 10.1002/mnfr.201800868. Epub 2019 Jan 2.


Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes.

Steinbrenner H, Micoogullari M, Hoang NA, Bergheim I, Klotz LO, Sies H.

Redox Biol. 2019 Jan;20:489-495. doi: 10.1016/j.redox.2018.11.004. Epub 2018 Nov 10.


Non-Alcoholic Fatty Liver Disease in Overweight Children: Role of Fructose Intake and Dietary Pattern.

Nier A, Brandt A, Conzelmann IB, Özel Y, Bergheim I.

Nutrients. 2018 Sep 19;10(9). pii: E1329. doi: 10.3390/nu10091329.


Iso-alpha acids from hops (Humulus lupulus) inhibit hepatic steatosis, inflammation, and fibrosis.

Mahli A, Koch A, Fresse K, Schiergens T, Thasler WE, Schönberger C, Bergheim I, Bosserhoff A, Hellerbrand C.

Lab Invest. 2018 Dec;98(12):1614-1626. doi: 10.1038/s41374-018-0112-x. Epub 2018 Aug 8.


Relations of gut liver axis components and gut microbiota in obese children with fatty liver: A pilot study.

Pierri L, Saggese P, Guercio Nuzio S, Troisi J, Di Stasi M, Poeta M, Savastano R, Marchese G, Tarallo R, Massa G, Ciccone V, Ziegenhardt D, Cavallo P, Bergheim I, Weisz A, Vajro P.

Clin Res Hepatol Gastroenterol. 2018 Sep;42(4):387-390. doi: 10.1016/j.clinre.2018.03.015. Epub 2018 Jul 10. No abstract available.


Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis.

Gaitantzi H, Meyer C, Rakoczy P, Thomas M, Wahl K, Wandrer F, Bantel H, Alborzinia H, Wölfl S, Ehnert S, Nüssler A, Bergheim I, Ciuclan L, Ebert M, Breitkopf-Heinlein K, Dooley S.

Cell Death Dis. 2018 Jan 19;9(2):51. doi: 10.1038/s41419-017-0071-y.


An iso-α-acid-rich extract from hops (Humulus lupulus) attenuates acute alcohol-induced liver steatosis in mice.

Hege M, Jung F, Sellmann C, Jin C, Ziegenhardt D, Hellerbrand C, Bergheim I.

Nutrition. 2018 Jan;45:68-75. doi: 10.1016/j.nut.2017.07.010. Epub 2017 Jul 27.


Oral Supplementation of Glutamine Attenuates the Progression of Nonalcoholic Steatohepatitis in C57BL/6J Mice.

Sellmann C, Baumann A, Brandt A, Jin CJ, Nier A, Bergheim I.

J Nutr. 2017 Nov;147(11):2041-2049. doi: 10.3945/jn.117.253815. Epub 2017 Sep 20.


Short-Term Intake of a Fructose-, Fat- and Cholesterol-Rich Diet Causes Hepatic Steatosis in Mice: Effect of Antibiotic Treatment.

Brandt A, Jin CJ, Nolte K, Sellmann C, Engstler AJ, Bergheim I.

Nutrients. 2017 Sep 14;9(9). pii: E1013. doi: 10.3390/nu9091013.


Markers of intestinal permeability are already altered in early stages of non-alcoholic fatty liver disease: Studies in children.

Nier A, Engstler AJ, Maier IB, Bergheim I.

PLoS One. 2017 Sep 7;12(9):e0183282. doi: 10.1371/journal.pone.0183282. eCollection 2017.


Voluntary distance running prevents TNF-mediated liver injury in mice through alterations of the intrahepatic immune milieu.

Huber Y, Gehrke N, Biedenbach J, Helmig S, Simon P, Straub BK, Bergheim I, Huber T, Schuppan D, Galle PR, Wörns MA, Schuchmann M, Schattenberg JM.

Cell Death Dis. 2017 Jun 22;8(6):e2893. doi: 10.1038/cddis.2017.266.


Plasminogen Activator Inhibitor-1 is Regulated Through Dietary Fat Intake and Heritability: Studies in Twins.

Engstler AJ, Frahnow T, Kruse M, Pfeiffer AFH, Bergheim I.

Twin Res Hum Genet. 2017 Aug;20(4):338-348. doi: 10.1017/thg.2017.36. Epub 2017 Jun 21.


Oral arginine supplementation protects female mice from the onset of non-alcoholic steatohepatitis.

Sellmann C, Degen C, Jin CJ, Nier A, Engstler AJ, Hasan Alkhatib D, De Bandt JP, Bergheim I.

Amino Acids. 2017 Jul;49(7):1215-1225. doi: 10.1007/s00726-017-2423-4. Epub 2017 Apr 22.


Treatment with alpha-galactosylceramide protects mice from early onset of nonalcoholic steatohepatitis: Role of intestinal barrier function.

Engstler AJ, Sellmann C, Jin CJ, Brandt A, Herz K, Priebs J, Bergheim I.

Mol Nutr Food Res. 2017 May;61(5). doi: 10.1002/mnfr.201600985. Epub 2017 Feb 22.


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