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Items: 1 to 20 of 330

1.

Mesenchymal Stem Cell Protection of Neurons against Glutamate Excitotoxicity Involves Reduction of NMDA-Triggered Calcium Responses and Surface GluR1, and Is Partly Mediated by TNF.

Papazian I, Kyrargyri V, Evangelidou M, Voulgari-Kokota A, Probert L.

Int J Mol Sci. 2018 Feb 25;19(3). pii: E651. doi: 10.3390/ijms19030651.

2.

A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of <i>N</i>-Methyl-D-aspartate Receptor.

Hu S, Hu H, Mak S, Cui G, Lee M, Shan L, Wang Y, Lin H, Zhang Z, Han Y.

Front Pharmacol. 2018 Feb 12;9:73. doi: 10.3389/fphar.2018.00073. eCollection 2018.

3.

Excitotoxicity in the pathogenesis of neurological and psychiatric disorders: Therapeutic implications.

Olloquequi J, Cornejo-Córdova E, Verdaguer E, Soriano FX, Binvignat O, Auladell C, Camins A.

J Psychopharmacol. 2018 Mar;32(3):265-275. doi: 10.1177/0269881118754680. Epub 2018 Feb 15.

PMID:
29444621
4.

Activation of caspase-6 and cleavage of caspase-6 substrates is an early event in NMDA receptor-mediated excitotoxicity.

Girling KD, Demers MJ, Laine J, Zhang S, Wang YT, Graham RK.

J Neurosci Res. 2018 Mar;96(3):391-406. doi: 10.1002/jnr.24153. Epub 2017 Nov 29.

PMID:
29193273
5.

Synaptic Activity Protects Neurons Against Calcium-Mediated Oxidation and Contraction of Mitochondria During Excitotoxicity.

Depp C, Bas-Orth C, Schroeder L, Hellwig A, Bading H.

Antioxid Redox Signal. 2017 Nov 14. doi: 10.1089/ars.2017.7092. [Epub ahead of print]

PMID:
28990420
6.

Tau exacerbates excitotoxic brain damage in an animal model of stroke.

Bi M, Gladbach A, van Eersel J, Ittner A, Przybyla M, van Hummel A, Chua SW, van der Hoven J, Lee WS, Müller J, Parmar J, Jonquieres GV, Stefen H, Guccione E, Fath T, Housley GD, Klugmann M, Ke YD, Ittner LM.

Nat Commun. 2017 Sep 7;8(1):473. doi: 10.1038/s41467-017-00618-0.

7.

Calpain-Dependent Degradation of Nucleoporins Contributes to Motor Neuron Death in a Mouse Model of Chronic Excitotoxicity.

Sugiyama K, Aida T, Nomura M, Takayanagi R, Zeilhofer HU, Tanaka K.

J Neurosci. 2017 Sep 6;37(36):8830-8844. doi: 10.1523/JNEUROSCI.0730-17.2017. Epub 2017 Aug 16.

8.

Phosphorylation of tau at Y18, but not tau-fyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture.

Miyamoto T, Stein L, Thomas R, Djukic B, Taneja P, Knox J, Vossel K, Mucke L.

Mol Neurodegener. 2017 May 19;12(1):41. doi: 10.1186/s13024-017-0176-x.

9.

Ecdysterones from Rhaponticum carthamoides (Willd.) Iljin reduce hippocampal excitotoxic cell loss and upregulate mTOR signaling in rats.

Wu J, Gao L, Shang L, Wang G, Wei N, Chu T, Chen S, Zhang Y, Huang J, Wang J, Lin R.

Fitoterapia. 2017 Jun;119:158-167. doi: 10.1016/j.fitote.2017.03.015. Epub 2017 Apr 2.

PMID:
28373010
10.

Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS.

Budni J, Molz S, Dal-Cim T, Martín-de-Saavedra MD, Egea J, Lopéz MG, Tasca CI, Rodrigues ALS.

Mol Neurobiol. 2018 Feb;55(2):1580-1589. doi: 10.1007/s12035-017-0425-6. Epub 2017 Feb 10.

PMID:
28185129
11.

Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid.

Saliba SW, Vieira EL, Santos RP, Candelario-Jalil E, Fiebich BL, Vieira LB, Teixeira AL, de Oliveira AC.

J Neuroinflammation. 2017 Jan 31;14(1):25. doi: 10.1186/s12974-017-0793-x.

12.

ASIC channel inhibition enhances excitotoxic neuronal death in an in vitro model of spinal cord injury.

Mazzone GL, Veeraraghavan P, Gonzalez-Inchauspe C, Nistri A, Uchitel OD.

Neuroscience. 2017 Feb 20;343:398-410. doi: 10.1016/j.neuroscience.2016.12.008. Epub 2016 Dec 19.

PMID:
28003157
14.

Anti-excitotoxic effects of cannabidiol are partly mediated by enhancement of NCX2 and NCX3 expression in animal model of cerebral ischemia.

Khaksar S, Bigdeli MR.

Eur J Pharmacol. 2017 Jan 5;794:270-279. doi: 10.1016/j.ejphar.2016.11.011. Epub 2016 Nov 14.

PMID:
27856160
15.

Galacto-N-biose is neuroprotective against glutamate-induced excitotoxicity in vitro.

Shinoda Y, Nakajima Y, Iguchi H, Tatsumi S, Kitaoka M, Nakajima M, Takahashi T, Fujiwara Y, Furuichi T.

Eur J Pharmacol. 2016 Nov 15;791:711-717. doi: 10.1016/j.ejphar.2016.10.010. Epub 2016 Oct 8.

PMID:
27729249
16.

Complement component 3 (C3) expression in the hippocampus after excitotoxic injury: role of C/EBPβ.

Hernandez-Encinas E, Aguilar-Morante D, Morales-Garcia JA, Gine E, Sanz-SanCristobal M, Santos A, Perez-Castillo A.

J Neuroinflammation. 2016 Oct 21;13(1):276.

17.

Diadenosine tetraphosphate (Ap<sub>4</sub>A) inhibits ATP-induced excitotoxicity: a neuroprotective strategy for traumatic spinal cord injury treatment.

Reigada D, Navarro-Ruiz RM, Caballero-López MJ, Del Águila Á, Muñoz-Galdeano T, Maza RM, Nieto-Díaz M.

Purinergic Signal. 2017 Mar;13(1):75-87. doi: 10.1007/s11302-016-9541-4. Epub 2016 Oct 19.

18.

Synthesis and Biological Evaluation of Novel Multi-target-Directed Benzazepines Against Excitotoxicity.

Machhi J, Prajapati N, Tripathi A, Parikh ZS, Kanhed AM, Patel K, Pillai PP, Giridhar R, Yadav MR.

Mol Neurobiol. 2017 Nov;54(9):6697-6722. doi: 10.1007/s12035-016-0184-9. Epub 2016 Oct 15.

PMID:
27744571
19.
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