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Items: 16


Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer.

Gottipati K, Holthauzen LM, Ruggli N, Choi KH.

J Virol. 2016 Aug 12;90(17):7740-7. doi: 10.1128/JVI.00318-16.


Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface.

Klema VJ, Ye M, Hindupur A, Teramoto T, Gottipati K, Padmanabhan R, Choi KH.

PLoS Pathog. 2016 Feb 19;12(2):e1005451. doi: 10.1371/journal.ppat.1005451.


Allosteric inhibitors of Coxsackie virus A24 RNA polymerase.

Schein CH, Rowold D, Choi KH.

Bioorg Med Chem. 2016 Feb 15;24(4):570-7. doi: 10.1016/j.bmc.2015.12.023.


Flaviviral Replication Complex: Coordination between RNA Synthesis and 5'-RNA Capping.

Klema VJ, Padmanabhan R, Choi KH.

Viruses. 2015 Aug 13;7(8):4640-56. doi: 10.3390/v7082837. Review.


Flavivirus RNA synthesis in vitro.

Padmanabhan R, Takhampunya R, Teramoto T, Choi KH.

Methods. 2015 Dec;91:20-34. doi: 10.1016/j.ymeth.2015.08.002. Review.


Sequence specificity for uridylylation of the viral peptide linked to the genome (VPg) of enteroviruses.

Schein CH, Ye M, Paul AV, Oberste MS, Chapman N, van der Heden van Noort GJ, Filippov DV, Choi KH.

Virology. 2015 Oct;484:80-5. doi: 10.1016/j.virol.2015.05.016.


Substitution of NS5 N-terminal domain of dengue virus type 2 RNA with type 4 domain caused impaired replication and emergence of adaptive mutants with enhanced fitness.

Teramoto T, Boonyasuppayakorn S, Handley M, Choi KH, Padmanabhan R.

J Biol Chem. 2014 Aug 8;289(32):22385-400. doi: 10.1074/jbc.M114.584466.


Use of small-angle X-ray scattering to investigate the structure and function of dengue virus NS3 and NS5.

Choi KH, Morais M.

Methods Mol Biol. 2014;1138:241-52. doi: 10.1007/978-1-4939-0348-1_15.


Autocatalytic activity and substrate specificity of the pestivirus N-terminal protease Npro.

Gottipati K, Acholi S, Ruggli N, Choi KH.

Virology. 2014 Mar;452-453:303-9. doi: 10.1016/j.virol.2014.01.026.


The structure of classical swine fever virus N(pro): a novel cysteine Autoprotease and zinc-binding protein involved in subversion of type I interferon induction.

Gottipati K, Ruggli N, Gerber M, Tratschin JD, Benning M, Bellamy H, Choi KH.

PLoS Pathog. 2013;9(10):e1003704. doi: 10.1371/journal.ppat.1003704.


Dengue virus nonstructural protein 5 adopts multiple conformations in solution.

Bussetta C, Choi KH.

Biochemistry. 2012 Jul 31;51(30):5921-31.


Viral polymerases.

Choi KH.

Adv Exp Med Biol. 2012;726:267-304. doi: 10.1007/978-1-4614-0980-9_12. Review.


Full-length Dengue virus RNA-dependent RNA polymerase-RNA/DNA complexes: stoichiometries, intrinsic affinities, cooperativities, base, and conformational specificities.

Szymanski MR, Jezewska MJ, Bujalowski PJ, Bussetta C, Ye M, Choi KH, Bujalowski W.

J Biol Chem. 2011 Sep 23;286(38):33095-108. doi: 10.1074/jbc.M111.255034.


RNA-dependent RNA polymerases from Flaviviridae.

Choi KH, Rossmann MG.

Curr Opin Struct Biol. 2009 Dec;19(6):746-51. doi: 10.1016/ Review.


Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation.

Szymanski MR, Fiebach AR, Tratschin JD, Gut M, Ramanujam VM, Gottipati K, Patel P, Ye M, Ruggli N, Choi KH.

J Mol Biol. 2009 Aug 14;391(2):438-49. doi: 10.1016/j.jmb.2009.06.040.


Insight into DNA and protein transport in double-stranded DNA viruses: the structure of bacteriophage N4.

Choi KH, McPartland J, Kaganman I, Bowman VD, Rothman-Denes LB, Rossmann MG.

J Mol Biol. 2008 May 2;378(3):726-36. doi: 10.1016/j.jmb.2008.02.059.

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