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Items: 1 to 20 of 45


BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation.

Li AG, Murphy EC, Culhane AC, Powell E, Wang H, Bronson RT, Von T, Giobbie-Hurder A, Gelman RS, Briggs KJ, Piwnica-Worms H, Zhao JJ, Kung AL, Kaelin WG Jr, Livingston DM.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9600-E9609. doi: 10.1073/pnas.1807112115. Epub 2018 Sep 25.


Concomitant p53 and PTEN immunoexpression to predict the risk of malignancy in endometrial polyps.

Abrão F, Modotti WP, Spadoto-Dias D, Bueloni-Dias FN, Leite NJ, Peres GF, Elias LV, Domingues MAC, Dias R.

Medicine (Baltimore). 2018 Sep;97(38):e12304. doi: 10.1097/MD.0000000000012304.


Regulation of PTEN expression by noncoding RNAs.

Li W, Zhang T, Guo L, Huang L.

J Exp Clin Cancer Res. 2018 Sep 10;37(1):223. doi: 10.1186/s13046-018-0898-9. Review.


PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis.

Xu W, Yang Z, Xie C, Zhu Y, Shu X, Zhang Z, Li N, Chai N, Zhang S, Wu K, Nie Y, Lu N.

J Exp Clin Cancer Res. 2018 Aug 22;37(1):198. doi: 10.1186/s13046-018-0795-2.


Clinical utility of assessing PTEN and ERG protein expression in prostate cancer patients: a proposed method for risk stratification.

Bismar TA, Hegazy S, Feng Z, Yu D, Donnelly B, Palanisamy N, Trock BJ.

J Cancer Res Clin Oncol. 2018 Nov;144(11):2117-2125. doi: 10.1007/s00432-018-2730-5. Epub 2018 Aug 12.


Mangiferin inhibits high-fat diet induced vascular injury via regulation of PTEN/AKT/eNOS pathway.

Jiang F, Zhang DL, Jia M, Hao WH, Li YJ.

J Pharmacol Sci. 2018 Jul;137(3):265-273. doi: 10.1016/j.jphs.2018.07.004. Epub 2018 Jul 10.


BMI1 and PTEN are key determinants of breast cancer therapy: A plausible therapeutic target in breast cancer.

M JR, S V.

Gene. 2018 Dec 15;678:302-311. doi: 10.1016/j.gene.2018.08.022. Epub 2018 Aug 8. Review.


PTEN-GSK3β-MOB1 axis controls neurite outgrowth in vitro and in vivo.

Song Z, Han X, Zou H, Zhang B, Ding Y, Xu X, Zeng J, Liu J, Gong A.

Cell Mol Life Sci. 2018 Dec;75(23):4445-4464. doi: 10.1007/s00018-018-2890-0. Epub 2018 Aug 1.


Succinate Accumulation Is Associated with a Shift of Mitochondrial Respiratory Control and HIF-1α Upregulation in PTEN Negative Prostate Cancer Cells.

Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE.

Int J Mol Sci. 2018 Jul 21;19(7). pii: E2129. doi: 10.3390/ijms19072129.


Sirt3-mediated mitochondrial fission regulates the colorectal cancer stress response by modulating the Akt/PTEN signalling pathway.

Wang Y, Sun X, Ji K, Du L, Xu C, He N, Wang J, Liu Y, Liu Q.

Biomed Pharmacother. 2018 Sep;105:1172-1182. doi: 10.1016/j.biopha.2018.06.071. Epub 2018 Jun 21.


microRNA-19a-3p promotes tumor metastasis and chemoresistance through the PTEN/Akt pathway in hepatocellular carcinoma.

Jiang XM, Yu XN, Liu TT, Zhu HR, Shi X, Bilegsaikhan E, Guo HY, Song GQ, Weng SQ, Huang XX, Dong L, Janssen HLA, Shen XZ, Zhu JM.

Biomed Pharmacother. 2018 Sep;105:1147-1154. doi: 10.1016/j.biopha.2018.06.097. Epub 2018 Jun 21.


Knockdown of NUPR1 inhibits the growth of U266 and RPMI8226 multiple myeloma cell lines via activating PTEN and caspase activation‑dependent apoptosis.

Zeng C, Li X, Li A, Yi B, Peng X, Huang X, Chen J.

Oncol Rep. 2018 Sep;40(3):1487-1494. doi: 10.3892/or.2018.6544. Epub 2018 Jul 4.


Suppression of Elk1 inhibits thyroid cancer progression by mediating PTEN expression.

Kong Y, Yin J, Fu Y, Chen Y, Zhou Y, Geng X.

Oncol Rep. 2018 Sep;40(3):1769-1776. doi: 10.3892/or.2018.6554. Epub 2018 Jul 10.


PTEN enhances nasal epithelial cell resistance to TNFα‑induced inflammatory injury by limiting mitophagy via repression of the TLR4‑JNK‑Bnip3 pathway.

Li M, Yang X, Wang S.

Mol Med Rep. 2018 Sep;18(3):2973-2986. doi: 10.3892/mmr.2018.9264. Epub 2018 Jul 9.


Downregulation of microRNA‑21 expression inhibits proliferation, and induces G1 arrest and apoptosis via the PTEN/AKT pathway in SKM‑1 cells.

Li G, Song Y, Li G, Ren J, Xie J, Zhang Y, Gao F, Mu J, Dai J.

Mol Med Rep. 2018 Sep;18(3):2771-2779. doi: 10.3892/mmr.2018.9255. Epub 2018 Jul 5.


MicroRNA‑655 suppresses cell proliferation and invasion in oral squamous cell carcinoma by directly targeting metadherin and regulating the PTEN/AKT pathway.

Wang Q, Lv L, Li Y, Ji H.

Mol Med Rep. 2018 Sep;18(3):3106-3114. doi: 10.3892/mmr.2018.9292. Epub 2018 Jul 16.


MicroRNA-760 Inhibits Doxorubicin Resistance in Hepatocellular Carcinoma through Regulating Notch1/Hes1-PTEN/Akt Signaling Pathway.

Tian T, Fu X, Lu J, Ruan Z, Nan K, Yao Y, Yang Y.

J Biochem Mol Toxicol. 2018 Aug;32(8):e22167. doi: 10.1002/jbt.22167. Epub 2018 Jul 3.


MicroRNA‑26a protects vascular smooth muscle cells against H2O2‑induced injury through activation of the PTEN/AKT/mTOR pathway.

Peng J, He X, Zhang L, Liu P.

Int J Mol Med. 2018 Sep;42(3):1367-1378. doi: 10.3892/ijmm.2018.3746. Epub 2018 Jun 27.


miR‑214 mediates vascular inflammation and apoptosis via PTEN expression.

Wang M, Liu M, Ni T, Liu Q.

Mol Med Rep. 2018 Aug;18(2):2229-2236. doi: 10.3892/mmr.2018.9185. Epub 2018 Jun 18.


MiR-374b Promotes Proliferation and Inhibits Apoptosis of Human GIST Cells by Inhibiting PTEN through Activation of the PI3K/Akt Pathway.

Long ZW, Wu JH, Cai-Hong, Wang YN, Zhou Y.

Mol Cells. 2018 Jun;41(6):532-544. doi: 10.14348/molcells.2018.2211. Epub 2018 Jun 14.

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