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1,2,3-Triazole-containing hybrids with potential antibacterial activity against ESKAPE pathogens.
Deng C, Yan H, Wang J, Liu K, Liu BS, Shi YM. Deng C, et al. Eur J Med Chem. 2022 Dec 15;244:114888. doi: 10.1016/j.ejmech.2022.114888. Epub 2022 Oct 29. Eur J Med Chem. 2022. PMID: 36334453 Review.
Notably, several 1,2,3-triazole-containing hybrids which are exemplified by cefatrizine, radezolid and tazobactam have already approved as antibiotics to treat infections caused by various organisms including ESKAPE pathogens and their drug-resistant forms, revealing that …
Notably, several 1,2,3-triazole-containing hybrids which are exemplified by cefatrizine, radezolid and tazobactam have already approv …
Oxazolidinone Antibiotics: Chemical, Biological and Analytical Aspects.
Foti C, Piperno A, Scala A, Giuffrè O. Foti C, et al. Molecules. 2021 Jul 14;26(14):4280. doi: 10.3390/molecules26144280. Molecules. 2021. PMID: 34299555 Free PMC article. Review.
Here, the main features of oxazolidinone antibiotics licensed or under development, such as Linezolid, Sutezolid, Eperezolid, Radezolid, Contezolid, Posizolid, Tedizolid, Delpazolid and TBI-223, are discussed. ...
Here, the main features of oxazolidinone antibiotics licensed or under development, such as Linezolid, Sutezolid, Eperezolid, Radezolid …
Investigational and Experimental Drugs for Community-Acquired Pneumonia: the Current Evidence.
Sellarès-Nadal J, Burgos J, Falcó V, Almirante B. Sellarès-Nadal J, et al. J Exp Pharmacol. 2020 Nov 19;12:529-538. doi: 10.2147/JEP.S259286. eCollection 2020. J Exp Pharmacol. 2020. PMID: 33239925 Free PMC article. Review.
These include zabofloxacin, aravofloxacin, nafithromycin, TP-271, gepotidacin, radezolid, delpazolid, and CAL02. The preliminary results of these clinical trials allow us to assure that most of these drugs may play a role in the future treatment of CAP....
These include zabofloxacin, aravofloxacin, nafithromycin, TP-271, gepotidacin, radezolid, delpazolid, and CAL02. The preliminary resu …
Analytical Methodologies for the Estimation of Oxazolidinone Antibiotics as Key Members of anti-MRSA Arsenal: A Decade in Review.
El-Kimary EI, Allam AN, Khafagy ES, Hegazy WAH. El-Kimary EI, et al. Crit Rev Anal Chem. 2023 Jun 28:1-30. doi: 10.1080/10408347.2023.2228902. Online ahead of print. Crit Rev Anal Chem. 2023. PMID: 37378883 Review.
This group include approved marketed members (tedizolid, linezolid and contezolid) or those under development (delpazlolid, radezolid and sutezolid). Due to the significant impact of this class, larger number of analytical methods were required to meet the needs of both cl …
This group include approved marketed members (tedizolid, linezolid and contezolid) or those under development (delpazlolid, radezolid …
The Antibacterial Activity of 1,2,3-triazole- and 1,2,4-Triazole-containing Hybrids against Staphylococcus aureus: An Updated Review (2020- Present).
Li J, Zhang J. Li J, et al. Curr Top Med Chem. 2022;22(1):41-63. doi: 10.2174/1568026621666211111160332. Curr Top Med Chem. 2022. PMID: 34766892 Review.
Moreover, 1,2,3-triazole-cephalosporin hybrid cefatrizine, 1,2,3- triazole-oxazolidinone hybrid radezolid, and 1,2,4-triazolo[1,5-a]pyrimidine hybrid essramycin, have already been used in clinical practice to treat bacterial infections. ...
Moreover, 1,2,3-triazole-cephalosporin hybrid cefatrizine, 1,2,3- triazole-oxazolidinone hybrid radezolid, and 1,2,4-triazolo[1,5-a]p …