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Items: 1 to 20 of 171

1.

Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched.

Zhang Y, Bulkley DP, Xin Y, Roberts KJ, Asarnow DE, Sharma A, Myers BR, Cho W, Cheng Y, Beachy PA.

Cell. 2018 Nov 1. pii: S0092-8674(18)31379-5. doi: 10.1016/j.cell.2018.10.026. [Epub ahead of print]

PMID:
30415841
2.

The Lysosomal Transcription Factor TFEB Represses Myelination Downstream of the Rag-Ragulator Complex.

Meireles AM, Shen K, Zoupi L, Iyer H, Bouchard EL, Williams A, Talbot WS.

Dev Cell. 2018 Nov 5;47(3):319-330.e5. doi: 10.1016/j.devcel.2018.10.003.

PMID:
30399334
3.

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.

Haney MS, Bohlen CJ, Morgens DW, Ousey JA, Barkal AA, Tsui CK, Ego BK, Levin R, Kamber RA, Collins H, Tucker A, Li A, Vorselen D, Labitigan L, Crane E, Boyle E, Jiang L, Chan J, Rincón E, Greenleaf WJ, Li B, Snyder MP, Weissman IL, Theriot JA, Collins SR, Barres BA, Bassik MC.

Nat Genet. 2018 Nov 5. doi: 10.1038/s41588-018-0254-1. [Epub ahead of print]

PMID:
30397336
4.

Publisher Correction: Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma.

Kahn SA, Wang X, Nitta RT, Gholamin S, Theruvath J, Hutter G, Azad TD, Wadi L, Bolin S, Ramaswamy V, Esparza R, Liu KW, Edwards M, Swartling FJ, Sahoo D, Li G, Wechsler-Reya RJ, Reimand J, Cho YJ, Taylor MD, Weissman IL, Mitra SS, Cheshier SH.

Nat Commun. 2018 Nov 2;9(1):4651. doi: 10.1038/s41467-018-07182-1.

5.

CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Lymphoma.

Advani R, Flinn I, Popplewell L, Forero A, Bartlett NL, Ghosh N, Kline J, Roschewski M, LaCasce A, Collins GP, Tran T, Lynn J, Chen JY, Volkmer JP, Agoram B, Huang J, Majeti R, Weissman IL, Takimoto CH, Chao MP, Smith SM.

N Engl J Med. 2018 Nov 1;379(18):1711-1721. doi: 10.1056/NEJMoa1807315.

PMID:
30380386
6.

Arabidopsis ACC Oxidase 1 Coordinated by Multiple Signals Mediates Ethylene Biosynthesis and Is Involved in Root Development.

Park CH, Roh J, Youn JH, Son SH, Park JH, Kim SY, Kim TW, Kim SK.

Mol Cells. 2018 Oct 31;41(10):923-932. doi: 10.14348/molcells.2018.0092. Epub 2018 Oct 1.

7.

Cilia-Associated Oxysterols Activate Smoothened.

Raleigh DR, Sever N, Choksi PK, Sigg MA, Hines KM, Thompson BM, Elnatan D, Jaishankar P, Bisignano P, Garcia-Gonzalo FR, Krup AL, Eberl M, Byrne EFX, Siebold C, Wong SY, Renslo AR, Grabe M, McDonald JG, Xu L, Beachy PA, Reiter JF.

Mol Cell. 2018 Oct 18;72(2):316-327.e5. doi: 10.1016/j.molcel.2018.08.034.

PMID:
30340023
8.

Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells.

Gupta I, Collier PG, Haase B, Mahfouz A, Joglekar A, Floyd T, Koopmans F, Barres B, Smit AB, Sloan SA, Luo W, Fedrigo O, Ross ME, Tilgner HU.

Nat Biotechnol. 2018 Oct 15. doi: 10.1038/nbt.4259. [Epub ahead of print]

PMID:
30320766
9.

Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma.

Kahn SA, Wang X, Nitta RT, Gholamin S, Theruvath J, Hutter G, Azad TD, Wadi L, Bolin S, Ramaswamy V, Esparza R, Liu KW, Edwards M, Swartling FJ, Sahoo D, Li G, Wechsler-Reya RJ, Reimand J, Cho YJ, Taylor MD, Weissman IL, Mitra SS, Cheshier SH.

Nat Commun. 2018 Oct 8;9(1):4121. doi: 10.1038/s41467-018-06564-9. Erratum in: Nat Commun. 2018 Nov 2;9(1):4651.

10.

Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1.

Lananna BV, Nadarajah CJ, Izumo M, Cedeño MR, Xiong DD, Dimitry J, Tso CF, McKee CA, Griffin P, Sheehan PW, Haspel JA, Barres BA, Liddelow SA, Takahashi JS, Karatsoreos IN, Musiek ES.

Cell Rep. 2018 Oct 2;25(1):1-9.e5. doi: 10.1016/j.celrep.2018.09.015.

11.

A Small Molecule TrkB Neurotrophin Receptor Partial Agonist as Possible Treatment for Experimental Nonarteritic Anterior Ischemic Optic Neuropathy.

Ali Shariati M, Kumar V, Yang T, Chakraborty C, Barres BA, Longo FM, Liao YJ.

Curr Eye Res. 2018 Dec;43(12):1489-1499. doi: 10.1080/02713683.2018.1508726. Epub 2018 Oct 1.

PMID:
30273053
12.

Discovering human diabetes-risk gene function with genetics and physiological assays.

Peiris H, Park S, Louis S, Gu X, Lam JY, Asplund O, Ippolito GC, Bottino R, Groop L, Tucker H, Kim SK.

Nat Commun. 2018 Sep 21;9(1):3855. doi: 10.1038/s41467-018-06249-3.

13.

Identification of the Human Skeletal Stem Cell.

Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, Leavitt T, Lu WJ, Nguyen A, Conley SD, Salhotra A, Ambrosi TH, Borrelli MR, Siebel T, Chan K, Schallmoser K, Seita J, Sahoo D, Goodnough H, Bishop J, Gardner M, Majeti R, Wan DC, Goodman S, Weissman IL, Chang HY, Longaker MT.

Cell. 2018 Sep 20;175(1):43-56.e21. doi: 10.1016/j.cell.2018.07.029.

PMID:
30241615
14.

A sequence-based, deep learning model accurately predicts RNA splicing branchpoints.

Paggi JM, Bejerano G.

RNA. 2018 Sep 17. pii: rna.066290.118. doi: 10.1261/rna.066290.118. [Epub ahead of print]

PMID:
30224349
15.

Identification of PAmKate as a Red Photoactivatable Fluorescent Protein for Cryogenic Super-Resolution Imaging.

Dahlberg PD, Sartor AM, Wang J, Saurabh S, Shapiro L, Moerner WE.

J Am Chem Soc. 2018 Oct 3;140(39):12310-12313. doi: 10.1021/jacs.8b05960. Epub 2018 Sep 20.

PMID:
30222332
16.

Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma.

Purzner T, Purzner J, Buckstaff T, Cozza G, Gholamin S, Rusert JM, Hartl TA, Sanders J, Conley N, Ge X, Langan M, Ramaswamy V, Ellis L, Litzenburger U, Bolin S, Theruvath J, Nitta R, Qi L, Li XN, Li G, Taylor MD, Wechsler-Reya RJ, Pinna LA, Cho YJ, Fuller MT, Elias JE, Scott MP.

Sci Signal. 2018 Sep 11;11(547). pii: eaau5147. doi: 10.1126/scisignal.aau5147.

PMID:
30206138
17.

Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal.

Marian CA, Stoszko M, Wang L, Leighty MW, de Crignis E, Maschinot CA, Gatchalian J, Carter BC, Chowdhury B, Hargreaves DC, Duvall JR, Crabtree GR, Mahmoudi T, Dykhuizen EC.

Cell Chem Biol. 2018 Aug 23. pii: S2451-9456(18)30270-8. doi: 10.1016/j.chembiol.2018.08.004. [Epub ahead of print]

PMID:
30197195
18.

Screening for genes that regulate the differentiation of human megakaryocytic lineage cells.

Zhu F, Feng M, Sinha R, Seita J, Mori Y, Weissman IL.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9308-E9316. doi: 10.1073/pnas.1805434115. Epub 2018 Aug 27.

PMID:
30150396
19.

A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas.

Arda HE, Tsai J, Rosli YR, Giresi P, Bottino R, Greenleaf WJ, Chang HY, Kim SK.

Cell Syst. 2018 Sep 26;7(3):310-322.e4. doi: 10.1016/j.cels.2018.07.007. Epub 2018 Aug 22.

PMID:
30145115
20.

Independent erosion of conserved transcription factor binding sites points to shared hindlimb, vision and external testes loss in different mammals.

Berger MJ, Wenger AM, Guturu H, Bejerano G.

Nucleic Acids Res. 2018 Oct 12;46(18):9299-9308. doi: 10.1093/nar/gky741.

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