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Items: 1 to 20 of 149

1.

A functional enrichment test for molecular convergent evolution finds a clear protein-coding signal in echolocating bats and whales.

Marcovitz A, Turakhia Y, Chen HI, Gloudemans M, Braun BA, Wang H, Bejerano G.

Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21094-21103. doi: 10.1073/pnas.1818532116. Epub 2019 Sep 30.

PMID:
31570615
2.

Emergent high fatality lung disease in systemic juvenile arthritis.

Saper VE, Chen G, Deutsch GH, Guillerman RP, Birgmeier J, Jagadeesh K, Canna S, Schulert G, Deterding R, Xu J, Leung AN, Bouzoubaa L, Abulaban K, Baszis K, Behrens EM, Birmingham J, Casey A, Cidon M, Cron RQ, De A, De Benedetti F, Ferguson I, Fishman MP, Goodman SI, Graham TB, Grom AA, Haines K, Hazen M, Henderson LA, Ho A, Ibarra M, Inman CJ, Jerath R, Khawaja K, Kingsbury DJ, Klein-Gitelman M, Lai K, Lapidus S, Lin C, Lin J, Liptzin DR, Milojevic D, Mombourquette J, Onel K, Ozen S, Perez M, Phillippi K, Prahalad S, Radhakrishna S, Reinhardt A, Riskalla M, Rosenwasser N, Roth J, Schneider R, Schonenberg-Meinema D, Shenoi S, Smith JA, Sönmez HE, Stoll ML, Towe C, Vargas SO, Vehe RK, Young LR, Yang J, Desai T, Balise R, Lu Y, Tian L, Bejerano G, Davis MM, Khatri P, Mellins ED; Childhood Arthritis and Rheumatology Research Alliance Registry Investigators.

Ann Rheum Dis. 2019 Sep 27. pii: annrheumdis-2019-216040. doi: 10.1136/annrheumdis-2019-216040. [Epub ahead of print]

PMID:
31562126
3.

Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma.

Gholamin S, Youssef OA, Rafat M, Esparza R, Kahn S, Shahin M, Giaccia AJ, Graves EE, Weissman I, Mitra S, Cheshier SH.

Innate Immun. 2019 Sep 23:1753425919876690. doi: 10.1177/1753425919876690. [Epub ahead of print] No abstract available.

PMID:
31547758
4.

Dysregulated integrin αVβ3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis.

Wang Q, Onuma K, Liu C, Wong H, Bloom MS, Elliott EE, Cao RR, Hu N, Lingampalli N, Sharpe O, Zhao X, Sohn DH, Lepus CM, Sokolove J, Mao R, Cisar CT, Raghu H, Chu CR, Giori NJ, Willingham SB, Prohaska SS, Cheng Z, Weissman IL, Robinson WH.

JCI Insight. 2019 Sep 19;4(18). pii: 128616. doi: 10.1172/jci.insight.128616.

5.

The Golgi Outpost Protein TPPP Nucleates Microtubules and Is Critical for Myelination.

Fu MM, McAlear TS, Nguyen H, Oses-Prieto JA, Valenzuela A, Shi RD, Perrino JJ, Huang TT, Burlingame AL, Bechstedt S, Barres BA.

Cell. 2019 Sep 19;179(1):132-146.e14. doi: 10.1016/j.cell.2019.08.025. Epub 2019 Sep 12.

PMID:
31522887
6.

Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation.

Tsai JM, Shoham M, Fernhoff NB, George BM, Marjon KD, McCracken MN, Kao KS, Sinha R, Volkmer AK, Miyanishi M, Seita J, Rinkevich Y, Weissman IL.

Blood Adv. 2019 Sep 24;3(18):2713-2721. doi: 10.1182/bloodadvances.2018024026.

7.

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology.

Tanigawa Y, Li J, Justesen JM, Horn H, Aguirre M, DeBoever C, Chang C, Narasimhan B, Lage K, Hastie T, Park CY, Bejerano G, Ingelsson E, Rivas MA.

Nat Commun. 2019 Sep 6;10(1):4064. doi: 10.1038/s41467-019-11953-9.

8.

Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome.

Greenberg RS, Long HK, Swigut T, Wysocka J.

Cell. 2019 Sep 5;178(6):1421-1436.e24. doi: 10.1016/j.cell.2019.08.002.

PMID:
31491386
9.

AVADA: toward automated pathogenic variant evidence retrieval directly from the full-text literature.

Birgmeier J, Deisseroth CA, Hayward LE, Galhardo LMT, Tierno AP, Jagadeesh KA, Stenson PD, Cooper DN, Bernstein JA, Haeussler M, Bejerano G.

Genet Med. 2019 Aug 30. doi: 10.1038/s41436-019-0643-6. [Epub ahead of print]

PMID:
31467448
10.

Phagocytosis checkpoints as new targets for cancer immunotherapy.

Feng M, Jiang W, Kim BYS, Zhang CC, Fu YX, Weissman IL.

Nat Rev Cancer. 2019 Oct;19(10):568-586. doi: 10.1038/s41568-019-0183-z. Epub 2019 Aug 28. Review.

PMID:
31462760
11.

The GABA receptor GABRR1 is expressed on and functional in hematopoietic stem cells and megakaryocyte progenitors.

Zhu F, Feng M, Sinha R, Murphy MP, Luo F, Kao KS, Szade K, Seita J, Weissman IL.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18416-18422. doi: 10.1073/pnas.1906251116. Epub 2019 Aug 26.

PMID:
31451629
12.

De novo mutations in mitochondrial DNA of iPSCs produce immunogenic neoepitopes in mice and humans.

Deuse T, Hu X, Agbor-Enoh S, Koch M, Spitzer MH, Gravina A, Alawi M, Marishta A, Peters B, Kosaloglu-Yalcin Z, Yang Y, Rajalingam R, Wang D, Nashan B, Kiefmann R, Reichenspurner H, Valantine H, Weissman IL, Schrepfer S.

Nat Biotechnol. 2019 Oct;37(10):1137-1144. doi: 10.1038/s41587-019-0227-7. Epub 2019 Aug 19.

PMID:
31427818
13.

Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes.

Ghosn E, Yoshimoto M, Nakauchi H, Weissman IL, Herzenberg LA.

Development. 2019 Aug 1;146(15). pii: dev170571. doi: 10.1242/dev.170571. Review.

PMID:
31371526
14.

CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy.

Barkal AA, Brewer RE, Markovic M, Kowarsky M, Barkal SA, Zaro BW, Krishnan V, Hatakeyama J, Dorigo O, Barkal LJ, Weissman IL.

Nature. 2019 Aug;572(7769):392-396. doi: 10.1038/s41586-019-1456-0. Epub 2019 Jul 31.

PMID:
31367043
15.

Spatial Regulation of Polo-Like Kinase Activity During Caenorhabditis elegans Meiosis by the Nucleoplasmic HAL-2/HAL-3 Complex.

Roelens B, Barroso C, Montoya A, Cutillas P, Zhang W, Woglar A, Girard C, Martinez-Perez E, Villeneuve AM.

Genetics. 2019 Sep;213(1):79-96. doi: 10.1534/genetics.119.302479. Epub 2019 Jul 25.

PMID:
31345995
16.

Asymmetric division yields progeny cells with distinct modes of regulating cell cycle-dependent chromosome methylation.

Zhou X, Wang J, Herrmann J, Moerner WE, Shapiro L.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15661-15670. doi: 10.1073/pnas.1906119116. Epub 2019 Jul 17.

PMID:
31315982
17.

Perspectives on the role of Wnt biology in cancer.

Mirabelli CK, Nusse R, Tuveson DA, Williams BO.

Sci Signal. 2019 Jul 9;12(589). pii: eaay4494. doi: 10.1126/scisignal.aay4494. Review.

PMID:
31289213
18.

Single-cell analysis reveals T cell infiltration in old neurogenic niches.

Dulken BW, Buckley MT, Navarro Negredo P, Saligrama N, Cayrol R, Leeman DS, George BM, Boutet SC, Hebestreit K, Pluvinage JV, Wyss-Coray T, Weissman IL, Vogel H, Davis MM, Brunet A.

Nature. 2019 Jul;571(7764):205-210. doi: 10.1038/s41586-019-1362-5. Epub 2019 Jul 3.

PMID:
31270459
19.

Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.

Deshpande I, Liang J, Hedeen D, Roberts KJ, Zhang Y, Ha B, Latorraca NR, Faust B, Dror RO, Beachy PA, Myers BR, Manglik A.

Nature. 2019 Jul;571(7764):284-288. doi: 10.1038/s41586-019-1355-4. Epub 2019 Jul 1.

PMID:
31263273
20.

Topologically-guided continuous protein crystallization controls bacterial surface layer self-assembly.

Comerci CJ, Herrmann J, Yoon J, Jabbarpour F, Zhou X, Nomellini JF, Smit J, Shapiro L, Wakatsuki S, Moerner WE.

Nat Commun. 2019 Jun 21;10(1):2731. doi: 10.1038/s41467-019-10650-x.

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