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Items: 1 to 20 of 1731

1.

The application of the CRISPR-Cas9 genome editing machinery in food and agricultural science: Current status, future perspectives, and associated challenges.

Eş I, Gavahian M, Marti-Quijal FJ, Lorenzo JM, Khaneghah AM, Tsatsanis C, Kampranis SC, Barba FJ.

Biotechnol Adv. 2019 Feb 16. pii: S0734-9750(19)30025-4. doi: 10.1016/j.biotechadv.2019.02.006. [Epub ahead of print] Review.

PMID:
30779952
2.

Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer.

Dimitrakopoulou D, Tulkens D, Van Vlieberghe P, Vleminckx K.

Front Physiol. 2019 Feb 1;10:48. doi: 10.3389/fphys.2019.00048. eCollection 2019.

3.

Six6 and Six7 coordinately regulate expression of middle-wavelength opsins in zebrafish.

Ogawa Y, Shiraki T, Asano Y, Muto A, Kawakami K, Suzuki Y, Kojima D, Fukada Y.

Proc Natl Acad Sci U S A. 2019 Feb 14. pii: 201812884. doi: 10.1073/pnas.1812884116. [Epub ahead of print]

4.

Chemistry, manufacturing and controls for gene modified hematopoietic stem cells.

Soni S, Kohn DB.

Cytotherapy. 2019 Feb 8. pii: S1465-3249(18)30699-6. doi: 10.1016/j.jcyt.2018.12.001. [Epub ahead of print]

PMID:
30745225
5.

Combining CRISPR/Cas9-mediated knockout with genetic complementation for in-depth mechanistic studies in human ES cells.

Wang Z, Zhang Y, Lee YW, Ivanova NB.

Biotechniques. 2019 Jan;66(1):23-27. doi: 10.2144/btn-2018-0115.

6.

Gene Editing in Clinical Practice: Where are We?

Mittal RD.

Indian J Clin Biochem. 2019 Jan;34(1):19-25. doi: 10.1007/s12291-018-0804-4. Epub 2019 Jan 1. Review.

PMID:
30728669
7.

Application of genetics and biotechnology for improving medicinal plants.

Niazian M.

Planta. 2019 Feb 4. doi: 10.1007/s00425-019-03099-1. [Epub ahead of print] Review.

PMID:
30715560
8.

Design, Construction, and Application of Transcription Activation-Like Effectors.

Deng P, Carter S, Fink K.

Methods Mol Biol. 2019;1937:47-58. doi: 10.1007/978-1-4939-9065-8_3.

PMID:
30706389
9.

TALEN-Mediated Gene Editing of HBG in Human Hematopoietic Stem Cells Leads to Therapeutic Fetal Hemoglobin Induction.

Lux CT, Pattabhi S, Berger M, Nourigat C, Flowers DA, Negre O, Humbert O, Yang JG, Lee C, Jacoby K, Bernstein I, Kiem HP, Scharenberg A, Rawlings DJ.

Mol Ther Methods Clin Dev. 2018 Dec 31;12:175-183. doi: 10.1016/j.omtm.2018.12.008. eCollection 2019 Mar 15.

10.

Gene editing of the multi-copy H2A.B gene and its importance for fertility.

Anuar ND, Kurscheid S, Field M, Zhang L, Rebar E, Gregory P, Buchou T, Bowles J, Koopman P, Tremethick DJ, Soboleva TA.

Genome Biol. 2019 Jan 31;20(1):23. doi: 10.1186/s13059-019-1633-3.

11.

The role of metalloproteases in fertilisation in the ascidian Ciona robusta.

Nakazawa S, Shirae-Kurabayashi M, Sawada H.

Sci Rep. 2019 Jan 30;9(1):1009. doi: 10.1038/s41598-018-37721-1.

12.

DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.

Zhang K, Zhang Y, Xue J, Meng Q, Liu H, Bi C, Li C, Hu L, Yu H, Xiong T, Yang Y, Cui S, Bu Z, He X, Li J, Huang L, Weng C.

Cell Rep. 2019 Jan 29;26(5):1258-1272.e4. doi: 10.1016/j.celrep.2019.01.029.

13.

CRISPR/Cas9 technology as a potent molecular tool for gene therapy.

Karimian A, Azizian K, Parsian H, Rafieian S, Shafiei-Irannejad V, Kheyrollah M, Yousefi M, Majidinia M, Yousefi B.

J Cell Physiol. 2019 Jan 30. doi: 10.1002/jcp.27972. [Epub ahead of print] Review.

PMID:
30697727
14.

CRISPR/Cas9: A Novel Weapon in the Arsenal to Combat Plant Diseases.

Das A, Sharma N, Prasad M.

Front Plant Sci. 2019 Jan 15;9:2008. doi: 10.3389/fpls.2018.02008. eCollection 2018. Review.

15.

DNA-Free Genome Editing: Past, Present and Future.

Metje-Sprink J, Menz J, Modrzejewski D, Sprink T.

Front Plant Sci. 2019 Jan 14;9:1957. doi: 10.3389/fpls.2018.01957. eCollection 2018.

16.

[Research advance and application in the gene therapy of gene editing technologies].

Ren YX, Xiao RD, Lou XM, Fang XD.

Yi Chuan. 2019 Jan 20;41(1):18-27. doi: 10.16288/j.yczz.18-142. Chinese.

PMID:
30686782
17.

Generation of knockout mouse models of cyclin-dependent kinase inhibitors by engineered nuclease-mediated genome editing.

Park BM, Roh JI, Lee J, Lee HW.

Lab Anim Res. 2018 Dec;34(4):264-269. doi: 10.5625/lar.2018.34.4.264. Epub 2018 Dec 31.

18.

Loss of fibrinogen in zebrafish results in an asymptomatic embryonic hemostatic defect and synthetic lethality with thrombocytopenia.

Hu Z, Lavik KI, Liu Y, Vo AH, Richter CE, Di Paola J, Shavit JA.

J Thromb Haemost. 2019 Jan 21. doi: 10.1111/jth.14391. [Epub ahead of print]

PMID:
30663848
19.

A review on advanced methods in plant gene targeting.

Sanagala R, Moola AK, Bollipo Diana RK.

J Genet Eng Biotechnol. 2017 Dec;15(2):317-321. doi: 10.1016/j.jgeb.2017.07.004. Epub 2017 Aug 7. Review.

20.

Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases.

Chu C, Yang Z, Yang J, Yan L, Si C, Kang Y, Chen Z, Chen Y, Ji W, Niu Y.

BMC Biotechnol. 2019 Jan 15;19(1):7. doi: 10.1186/s12896-018-0494-2.

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